Investigation of the in vitro activity of lactic acid and its value for clinical practice in the treatment of vaginal infections
- Authors: Kira E.F.1, Rybalchenko O.V.2, Orlova O.G.2, Korshakova N.Y.3
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Affiliations:
- N.I. Pirogov National Medical and Surgical Center
- St. Petersburg State University
- N.I. Pirogov National Medical and Surgical Center, Ministry of Health of Russia
- Issue: No 11 (2017)
- Pages: 84-90
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248080
- DOI: https://doi.org/10.18565/aig.2017.11.84-91
- ID: 248080
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Abstract
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About the authors
Evgeniy Fedorovich Kira
N.I. Pirogov National Medical and Surgical Center
Email: profkira33@gmail.com
Honored worker of science of the Russian Federation, Honored doctor of the Russian Federation, Acad. RANS, MD, Professor, head of the Department of Women’s Diseases and Reproductive Health
Oksana Vladimirovna Rybalchenko
St. Petersburg State University
Email: OVR@inbox.ru
Doctor of Biological Sciences, Professor of the Department of Physiology, Head of the course “Microbiology, Virology and Immunology” at the Medical Faculty
Olga Gennadyevna Orlova
St. Petersburg State University
Email: oorlova18@mail.ru
Candidate of Biological Sciences, senior lecturer of the Department of Physiology at the Medical Faculty
N. Yu. Korshakova
N.I. Pirogov National Medical and Surgical Center, Ministry of Health of Russia
References
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- Кира Е.Ф., Прилепская В.Н., Костава М.Н., Гамирова Е.В., Довлетханова Э.Р., Душкина Е.А., Байрамова Г.Р., Трофимов Д.Ю., Донников А.Е. Современные подходы к выбору препарата локального действия в терапии бактериального вагиноза. Акушерство и гинекология. 2012; 7: 59-67. [Kira E.F., Prilepskaya V.N., Kostava M.N., Gamirova E.V., Dovletkhanova E.R., Dushkina E.A., Bairamova G.R., Trofimov D.Yu., Donnikov A.E. Modern approaches to the choice of locally applied drug in the therapy of bacterial vaginosis. Akusherstvo i ginekologiya/ Obstetrics and Gynecology. 2012; (7): 59-67. (in Russian)]
- Кира Е.Ф., Пекарев О.Г., Молчанов О.Л., Мальцева Л.И., Аксененко В.А., Селихова М.С., Летяева О.И., Минаев Н.Н., Коршакова Н.Ю. Сравнительный анализ эффективности и безопасности параллельного или последовательного сочетания метронидазола с молочной кислотой и двухэтапного метода метронидазол плюс пробиотик. Многоцентровое рандомизированное контролируемое исследование. Акушерство и гинекология. 2016; 9: 87-93. http://dx.doi.org/10.18565/aig.2016.9.87-93 [Kira E.F., Pekarev O.G., Molchanov O.L., Maltseva L.I., Aksenenko V.A., Selikhova M.S., Letyaeva O.I., Minaev N.N., Korshakova N.Yu. Comparative analysis of the efficiency and safety of parallel or sequential combination of metronidazole with lactic acid and a two-stage regimen including metronidazole plus a probiotic: A multicenter randomized controlled study. Akusherstvo i ginekologiya/Obstetrics and Gynecology. 2016; (9): 87-93. (in Russian) http:// dx.doi.org/10.18565/aig.2016.9.87-93]
- Andersch B., Brandberg A., Holst E. Treatment of bacterial vaginosis - an acid gel as an alternative to antibiotic treatment. Lakartidningen. 1990; 87(7): 465-8.
- Молчанов О.Л., Тимошенкова Ю.Л. О роли модуляции кис лотности влагалищной жидкости в терапии бактериального вагиноза. Гинекология. 2010; 12(1): 33-6. [Molchanov O.L., Timoshenkova Yu.L. On the role of the modulation of vaginal fluid acidity in the treatment of bacterial vaginosis. Ginekologiya. 2010; 12 (1): 33-36. (in Russian)]
- Гомберг М.А. Использование молочной кислоты для нормализации микрофлоры влагалища. Акушерство и гинекология. 2013; 9: 113-7. [Gomberg M.A. Use of lactic acid to normalize the vaginal microflora. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2013; (9): 113-7. (in Russian)]
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