High-frequency ultrasound study in the diagnosis of pointed warts on the external female genitalia


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Abstract

Objective. To optimize the diagnosis of pointed warts (PWs) on the external female genitalia. Subjects and methods. 98 patients who attended the V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, in the period from October 01, 2013 to December 01, 2014, were examined. All the women underwent high-frequency ultrasound study of the skin and mucosae of the external genitalia; extended colposcopy/vulvoscopy; photo fixation in the presence of PWs; their biopsy with subsequent morphological examination. Results. Echo signs characteristic of this nosological entity were established; these included homogeneous hypoechoic or anechoic masses with a deformed outer contour as pyramids, waves, or ridges, which were clearly demarcated from the underlying tissues; and their lower ultrasonic density. The combination of these signs allows for the diagnosis of PWs. To verify the diagnosis of PWs needed their morphological examination. The diagnostic sensitivity of the technique was 94%; a false-positive result was noted in 6% of cases. The specificity of the method was 100%. No case of a false-negative result was seen. Conclusion. The technique can enhance the efficiency of non-invasive diagnosis of PWs, detect subclinical lesions invisible to the naked eye, and determine the depth of the lesion on visible foci.

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About the authors

Gulnar Fazilevna Gasanova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: g_gasanova@oparina4.ru
postgraduate student

Elena Alekseevna Gorbunova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: flestagor@gmail.com
obstetrician-gynecologist

Aina Salavdinovna Saidova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_saidova@oparina4.ru
Candidate of Medical Sciences, obstetrician-gynecologist

Elena Genrikhovna Dodova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: adeli575@mail.ru
postgraduate student

Pavel Aleksandrovich Belkov

Anta-Med Clinic

Email: pavel@antamed.ru
dermatovenereologist

Bashirova Lala Bashirova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: leyla9296@hotmail.com
obstetrician-gynecologist

Apolikhina Inna Apolikhina

Research Center of Obstetrics, Gynecology, and Perinatology; I.M. Sechenov First Moscow State Medical University

Email: i_apolikhina@oparina4.ru
Doctor of Medical Sciences, Head of the Department of Aesthetic Gynecology and Rehabilitation; Professor of the Deparment of Obstetrics, Gynecology, Perinatology, and Reproductology, Institute of Professional Education

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