Effects of anthropogenic chemicals on reproduction
- Authors: Syrkasheva A.G.1, Dolgushina N.V.1, Yarotskaya E.L.1
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Affiliations:
- Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
- Issue: No 3 (2018)
- Pages: 16-21
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248146
- DOI: https://doi.org/10.18565/aig.2018.3.16-21
- ID: 248146
Cite item
Abstract
Objective. To carry out a systematic analysis of the data available in the current literature on the effects of some anthropogenic chemicals on human fertility, including on the effectiveness of assisted reproductive technology programs. Material and methods. The review includes the articles by foreign and Russian authors on this topic, which have been published in the Pubmed journals in the past 10 years. Results. The authors analyze the literature data on the effects of heavy metals, phthalates, and bisphenol A on various aspects of human reproductive function. They present data on the possible pathogenetic mechanisms of action of anthropogenic chemicals on the quality of gametes and the efficiency of treatment for infertility. Conclusion. It is necessary to further study the molecular mechanisms of negative action of toxicants on human fertility in order to determine management tactics in infertility patients.
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About the authors
Anastasia Grigorievna Syrkasheva
Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: a_syrkasheva@oparina4.ru
M.D., Ph.D., Researcher of the IVF Department
Nataliya Vitalievna Dolgushina
Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: n_dolgushina@oparina4.ru
M.D., Ph.D., M.P.H., Head of R&D Department
Ekaterina Lvovna Yarotskaya
Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: e_yarotskaya@oparina4.ru
M.D., Ph.D., Head of the Department for International Cooperation
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