Determination of umbilical cord blood acid-base status. Indications and techniques


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Abstract

Objective. To carry out a systems analysis of the data available in the current literature to assess the relationship between blood gases and pH values in a newborn infant and his/her status. Material and methods. The review includes the data of foreign and Russian articles published in the past 10 years and found in Pubmed on this topic. Results. The optimal solution is to apply two clamps to the umbilical cord and to take blood from the artery and vein, as this gives a more comprehensive idea of the cause and nature of hypoxia. A test should be carried out in the shortest possible time after blood collection, within one hour in some situations. Umbilical cord blood pH <7.0 and base deficit >12 mmol/l in combination with lactate >4.1 mmol/l are unfavorable prognostic factors for neonatal morbidity and long-term neurological disorders. Conclusion. The normal pH level excludes a causal relation between the course of labor and the subsequent development of hypoxic brain damage. Determination of umbilical cord blood gases is the most objective method to assess the baby’s status at birth.

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About the authors

Andrey Mikhailovich Prikhodko

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_prikhodko@oparina4.ru
PhD, physician of maternity department

Oleg Radomirovich Baev

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: o_baev@oparina4.ru
MD, Professor, Head of maternity department

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