The use of autoplasma, enriched with platelet-derived soluble factors, when carrying out the programs of in vitro fertilization (IFV) in patients with infertility and chronic endometritis


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Aim of study: To evaluate the effectiveness of autoplasma enriched with platelet-derived soluble factors in IVF cycles in patients with chronic endometritis in history. Materials and methods: The study took place in the period from 2017 to 2018. In IVF cycle autoplasma was not injected into the patients in Group I (n=43); on the 6th-10th day of the stimulated cycle, autoplasma enriched with platelet-derived soluble factors was injected into uterus in patients in group II (n=94). Inclusion criteria: the patients of reproductive age with infertility and chronic endometritis in history. Exclusion criteria: the patients with poor embryo quality. Results: Intrauterine injection of autologous plasma enriched with platelet-derived soluble factors increases up to 25% the success rate of embryo implantation during IVF procedure, as compared to traditional protocols.

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作者简介

Olga Doronina

Federal State Budget Institution "National Medical Research Center of Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov" Ministry of Health of the Russian Federation

Email: o_doronina@oparina4.ru
MD, Professor, Deputy Head of Medical Care Organization

Ella Deilidka

Healthcare Institution "Clinical Maternity Hospital № 2"

Email: deilidka@gmail.com
postgraduate student

参考

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