SCREENING FOR SERUM THYROID-STIMULATING HORMONE LEVELS IN INFERTILE WOMEN AS THE BASIS FOR PREDICTING THE OUTCOMES OF ASSISTED REPRODUCTIVE TECHNOLOGY PROGRAMS
- Authors: Paskar S.S.1, Kalugina A.S.1
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Affiliations:
- Acad. I.P. Pavlov First Saint Petersburg State Medical Unive
- Issue: No 8 (2019)
- Pages: 78-83
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248643
- DOI: https://doi.org/10.18565/aig.2019.8.78-83
- ID: 248643
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Open Access
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Abstract
Objective. To estimate the blood levels of thyroid-stimulating hormone (TSH) in infertile women and to evaluate its effect on the outcome of infertility treatment using assisted reproductive technologies (ART). Subjects and methods. The study sample included 171 married couples with a conf irmed diagnosis of Infertility, who referred for IVF and IVF/ICSI in the period 2016 to 2017. All the female patients underwent superovulation induction in the IVF and IVF/ICSI program. Serum TSH levels were measured one month before the start of an ART session. Results. Medical records indicated that autoimmune thyroiditis was diagnosed in 56 (32.7%) of the examinees. Patients with a TSH concentration of less than 1.4 mIU/ml were statistically significantly more frequently observed to have a positive infertility treatment outcome manifested by the highest proportion of ART deliveries (75.8%) than in those with that of more than 1.4 mIU/ml (p <0.001). Conclusion. The given results show that the decrease in blood TSH levels to less than 1.4 mIU/ml before ART is associated with the higher incidence of clinical pregnancy resulting from ART.
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About the authors
Svetlana S. Paskar
Acad. I.P. Pavlov First Saint Petersburg State Medical Unive
Email: paskarsvetlana@mail.ru
PhD student of the Department of Obstetrics and Gynecology and Neonatology 197022 Russia, Saint Petersburg, L’va Tolstogo st., 6/8
Alla S. Kalugina
Acad. I.P. Pavlov First Saint Petersburg State Medical UniveMD, Professor of the Department of Obstetrics and Gynecology and Neonatology 197022 Russia, Saint Petersburg, L’va Tolstogo st., 6/8
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