Preimplantation analysis of blastocyst transcriptome


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Abstract

This review is devoted to studying the influence of various factors on the expression of human blastocyst genes and to identifying transcripts that may be potential markers for successful implantation. Based on the data available in the world scientific literature, it has been shown that preimplantation analysis of the blastocyst transcriptome can be a tool for assessing the blastocyst implantation potential, which will be able to selectively transfer a single embryo during in vitro fertilization.

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About the authors

A. G Volkova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: agvolkova33@gmail.com
Cand. Biol. Sci.; Researcher 4, Oparin St., Moscow 117997, Russia

N. P Makarova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: np.makarova@gmail.com
BD; Leading Researcher 4, Oparin St., Moscow 117997, Russia

A. V Timofeeva

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v_timofeeva@oparina4.ru
Cand. Biol. Sci.; Head, Laboratory of Applied Transcriptomics 4, Oparin St., Moscow 117997, Russia

E. A Gorodnova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: e_gorodnova@oparina4.ru
Cand. Med. Sci.; Head, Center for Clinical Trials, Department for Organization of Research Activities 4, Oparin St., Moscow 117997, Russia

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