Iron deficiency states during pregnancy: prevention and treatment


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Abstract

Objective. To investigate the efficacy of prolonged-release ferrous sulphate (Tardyferon) in the prevention and treatment of iron deficiency states during pregnancy. Subjects and methods. A total of 159 singleton pregnant women with mild and moderate iron deficiency anemia (IDA) were followed up. All the patients were treated with a prolonged-release drug containing ferrous sulphate 247.325 mg, calculated in terms of iron 80 mg (Tardyferon). Results. The main blood count indicators were lower in pregnant women treated with Tardyferon. After a treatment cycle, complaints of shortness of breath and weakness disappeared in all the patients. Moreover, a clinical effect was achieved after 2 weeks of therapy whereas hematological parameters became normal 4 weeks later. In addition, all the patients continued treatment with prophylactic doses during a month after delivery, as recommended in the instructions for Tardyferon use. Conclusion. Prolonged-release ferrous sulphate (Tardyferon) is highly effective in preventing and treating IDA in pregnant women, leading to statistically significant normalization of ferrokinetic parameters and blood counts, improving the general condition of patients, and reducing obstetric and neonatal complications.

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About the authors

Victor L. Tyutyunnik

Perinatal Center, European Medical Center

Email: tioutiounnik@mail.ru
Dr.Med.Sci., Deputy Head Physician

Natalia E. Kan

Perinatal Center, European Medical Center; Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russi

Email: kan-med@mail.ru
Dr.Med.Sci., Head Physician of the Perinatal Center of European Medical Center, Professor at the Department of Obstetrics and Gynecology

Lia V. Khachatryan

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: leahkhachatryan@gmail.com
student

Igor I. Baranov

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russi

Email: i_baranov@oparina4.ru
MD, professor, head of the organizational and methodological department of the scientific and organizational support service of the Obstetrics and Gynecology

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