Blood and peritoneal fluid levels of soluble immunoregulatory molecules in patients with endometriosis
- Authors: Vtorushina V.V.1, Korotkova T.D.1, Krechetova L.V.1, Inviyaeva E.V.1, Van'ko L.V.1, Adamyan L.V.1
-
Affiliations:
- Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
- Issue: No 6 (2021)
- Pages: 85-94
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/249181
- DOI: https://doi.org/10.18565/aig.2021.6.85-94
- ID: 249181
Cite item
Abstract
Keywords
Full Text
About the authors
Valentina V. Vtorushina
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: v_vtorushina@oparina4.ru
Ph.D., Immunologist at the Laboratory of Clinical Immunology
Tatiana D. Korotkova
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: t_korotkova@oparina4.ru
Obstetrician-Gynecologist, Ph.D. Student at the Department of Gynecology
Lubov V. Krechetova
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: l_krechetova@oparina4.ru
Dr. Med. Sci., Head of the Laboratory of Clinical Immunology
Eugenia V. Inviyaeva
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: e_inviyaeva@oparina4.ru
Ph.D. (bio.sci.), Senior Researcher at the Laboratory of Clinical Immunology
Ludmila V. Van'ko
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: lvanko@oparina4.ru
Dr. Med. Sci., Professor, Leading Researcher at the Laboratory of Clinical Immunology
Leyla V. Adamyan
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: adamyanleila@gmail.com
Dr. Med. Sci., Academician of the RAS, Professor, Head of the Department of Gynecology, Deputy Director for Science
References
- Baranov V., Malysheva O., Yarmolinskaya M. Pathogenomics of endometriosis development. Int. J. Mol. Sci. 2018; 19(7). pii: E1852. https:dx.doi.org/10.3390/ijms19071852.
- Lin X., Dai Y., Xu W., Shi L., Jin X., Li C. et al. Hypoxia promotes ectopic adhesion ability of endometrial stromal cells via TGF-β1/smad signaling in endometriosis. Endocrinology. 2018; 159(4): 1630-41. https://dx.doi.org/10.1210/en.2017-03227.
- Reis F.M., Petraglia F., Taylor R.N. Endometriosis: hormone regulation and clinical consequences of chemotaxis and apoptosis. Hum. Reprod. Update. 2013; 19(4): 406-18. https:dx.doi.ois/10.1093/humupd/dmt010.
- Grimstad F.W., Decherney A. A review of the epigenetic contributions to endometriosis. Clin. Obstet. Gynecol. 2017; 60(3): 467-76. https:dx.doi.org/10.1097/GRF.0000000000000298.
- Lagana A.S., Vitale S.G., Salmeri F.M., Triolo O., Ban Frangez H., Vrtacnik-Bokal E. et al. Unus pro-omnibus, omnes pro uno: A novel, evidence-based, unifying theory for the pathogenesis of endometriosis. Med. Hypotheses. 2017; 103: 10-20. https:dx.doi.org/10.1016/j.mehy.2017.03.032.
- Анциферова Ю.С., Сотникова Н.Ю., Посисеева Л.В., Назаров С.Б. Иммунные механизмы развития генитального эндометриоза. Иваново; 2007. 314с.
- Ярмолинская М.И. Цитокиновый профиль перитонеальной жидкости и периферической крови больных с наружным генитальным эндометриозом. Журнал акушерства и женских болезней. 2008; 57(3): 30-4.
- Kobayashi H., Higashiura Y., Higetomi H., Kajihara H. Pathogenesis of endometriosis: The role of initial infection and subsequent sterile inflammation (Review). Mol. Med. Rep. 2014; 9(1): 9-15. https:dx.doi.org/10.3892/mmr.2013.1755.
- Ahn S.H., Edwards A.K., Singh S.S., Young S.L., Lessey B.A., Tayade C. IL-17A rontributes to the pathogenesis of endometriosis by triggering proinflammatory cytokines and angiogenic growth factors. J. Immunol. 2015; 195(6): 2591-600. https:dx.doi.org/10.4049/jimmunol.1501138.
- Barragan F., Irwin J.C., Balayan S., Erikson D.W., Chen J.C., Houshdaran S. et al. Human endometrial fibroblasts derived from mesenchymal progenitors inherit progesterone resistance and acquire an inflammatory phenotype in the endometrial niche in endometriosis. Biol. Reprod. 2016; 94(5): 118. https:dx.doi.org/10.1095/biolreprod.115.136010.
- Kalu E., Sumar N., Giannopoulos T., Patel P., Croucher C., Sherriff E., Bansal A. Cytokine profiles in serum and peritoneal fluid from infertile women with and without endometriosis. J. Obstet. Gynaecol. Res. 2007; 33(4): 490-5. https://dx.doi.org/10.1111/j.1447-0756.2007.00569.x.
- Cho K.R., Shih I.M. Ovarian cancer. Annu. Rev. Pathol. 2009; 4: 287-313. https:dx.doi.org/10.1146/annurev.pathol.4.110807.092246.
- Borrelli G.M., Kaufmann A.M., Abrao M.S., Mechsner S. Addition of MCP-1 and MIP-3P to the IL-8 appraisal in peritoneal fluid enhances the probability of identifying women with endometriosis. J. Reprod. Immunol. 2015; 109: 66-73. https:dx.doi.org/10.1016/j.jri.2015.01.003.
- Li S., Fu X., Wu T., Yang L., Hu C., Wu R. Role of interleukin-6 and its receptor in endometriosis. Med. Sci. Monit. 2017; 23: 3801-7. https://dx.doi.org/10.12659/MSM.905226.
- Llarena N.C., Richards E.J., Priyadarshini A., Fletcher D.,Bonfield T., Flyckt R.L. Characterizing the endometrial fluid cytokine profile in women with endometriosis. J. Assist. Reprod. Genet. 2020; 37(12): 2999-3006. https:dx.doi.org/10.1007/s10815-020-01989-y.
- Kang Y.J., Jeung I.C., Park A., Park Y.J., Jung H., Kim T.D. et al. An increased level of IL-6 suppresses NK cell activity in peritoneal fluid of patients with endometriosis via regulation of SHP-2 expression. Hum. Reprod. 2014; 29(10): 2176-89. https: dx.doi.org/10.1093/humrep/ deu172.
- Zhou W.J., Yang H.L., Shao J., Mei J., Chang K.K., Zhu R., Li M. Antiinflammatory cytokines in endometriosis. Cell. Mol. Life Sci. 2019; 76(11): 2111-32. https:dx.doi.org/10.1007/s00018-019-03056-x.
- Sipak-Szmigiel O., Wlodarski P., Ronin-Walknowska E., Niedzielski А., Karakiewicz B., Sluczanowska-Glqbowska S. et al. Serum and peritoneal fluid concentrations of soluble human leukocyte antigen, tumor necrosis factor alpha and interleukin 10 in patients with selected ovarian pathologies. J. Ovarian Res. 2017; 10: 25. https:dx.doi.org/10.1186/s13048-017-0320-9.
- Овакимян А. С., Кречетова Л.В., Вторушина В.В., Ванько Л.В., Козаченко И.Ф., Яроцкая Е.Л., Адамян Л.В. Содержание ИЛ-1в, ИЛ-8 и субстанции Р. в плазме крови и перитонеальной жидкости пациенток с различными формами наружного генитального эндометриоза и хронической тазовой болью. Акушерство и гинекология. 2015; 3: 79-86