The first experience with radical trachelectomy with uterine transposition in a patient with stage IB2 cervical cancer


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Abstract

Background. The priority direction of modern oncology is the development and introduction of organ-sparing treatments in cancer patients of reproductive age. Case report. The paper describes the first clinical experience with complex organ-sparing treatment according to the radical program for stage IB invasive cervical cancer in a reproductive-aged patient. A set of therapeutic measures has been proposed to ensure the functional safety of the uterus and appendages in the patient with cervical cancer who needs combination treatment, i.e. extended surgery followed by radiation or chemoradiotherapy to the pelvic area. The main technical technique was the uterine and appendage transposition that was performed as part of radical abdominal trachelectomy and could remove the utero-ovarian complex from the radiation load zone. In addition, the uterine locking apparatus was intraoperatively formed using a shape-memory implant made of titanium nickelide. The follow-up lasted 10 months and showed a satisfactory oncological efficacy. Conclusion. Thus, the described clinical case shows that organ-sparing surgery can be performed as part of comprehensive treatment using the radical program in a reproductive-aged patient with invasive cervical cancer.

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About the authors

Alyena L. Chernyshova

Research Institute of Oncology, Tomsk National Research Medical Center, Russian Academy of Sciences

Email: alacher@list.ru
Dr. Med. Sci., Professor of the RAS, leading researcher, Gynecology Department

Vitaly A. Antipov

M.V. Lomonosov Moscow State University

Email: gkb24@zdrav.mos.ru
Dr. Med. Sci., Head of Department of Female Reproductive System

Larisa A. Kolomiets

Research Institute of Oncology, Tomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical University, Ministry of Health of the Russian Federation

Email: kolomietsla@oncology.tomsk.ru
Dr. Med. Sci., Professor, Head of Gynecology Department

Vladimir I. Chernov

Research Institute of Oncology, Tomsk National Research Medical Center, Russian Academy of Sciences; Tomsk National Research Polytechnic University

Email: chernov@oncology.tomsk.ru
Dr. Med. Sci., Professor, Deputy Director for Research and Innovation, Head of Nuclear Medicine Department

Viktor E. Gyunter

Research Institute of Shape Memory Medical Materials and Implants

Email: tc77@mail2000.ru
Dr. Tech. Sci., Professor, Director

Ekaterina S. Marchenko

Research Institute of Shape Memory Medical Materials and Implants

Email: 89l3864l8l4@mail.ru
PhD in Technical Science, senior researcher

Timofei L. Chekalkin

Research Institute of Shape Memory Medical Materials and Implants

Email: tc77@mail2000.ru
PhD in Technical Science, senior researcher

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