Use of dehydroepiandrosterone in a patient with infertility and androgen deficiency


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Abstract

Background. Diminished ovarian reserve is one of the causes of female infertility and a poor response in ovulation induction. Despite advances in clinical embryological approaches and molecular genetic technologies, there are difficulties achieving pregnancy and the birth of a baby with the genetic material from a woman herself with diminished ovarian reserve. Case report. The paper describes a clinical case of the birth of a healthy baby in a patient with diminished ovarian reserve, infertility, and developing premature ovarian failure, who was prescribed dehydroepiandrosterone (DHEA) therapy. Conclusion. The presented clinical case cannot fully demonstrate DHEA treatment success in women with a sharply diminished ovarian reserve. Such situations occur sporadically without DHEA. In the author’s opinion, long-term (9-month) use of DHEA and careful monitoring of the ovaries and hormones are necessary to control treatment efficiency.

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About the authors

Alla A. Gavisova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: gavialla@yandex.ru
Ph.D., Senior Researcher of the 1st Gynecology Department

Marina A. Shevtsova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: marina_98l995@mail.ru
clinical resident of the 2nd year of study

Linda T. Tskhovrebova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: linda.tskhovrebova@mail.ru
clinical resident of the 2nd year of study

Nina D. Mikhaylova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: mihailnina@mail.ru
graduate student of the 1st year of study

Anastasiya V. Nikolaeva

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_nikolaeva@oparina4.ru
Ph.D., chief physician

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