Early amnion integrity impairment and amniotic band syndrome: diagnosis and pregnancy management tactics


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Abstract

Objective. To optimize diagnosis and pregnancy management tactics, including intrauterine correction, in early amnion integrity impairment and amniotic band syndrome (ABS). Subjects and methods. Fetal anatomical structures were assessed in 11 pregnant women with signs of early amnion integrity impairment at less than 14 weeks’ gestation, as well as in 5 patients with signs of ABS in the second trimester of pregnancy. The investigation was conducted on Voluson E8 and Voluson E10 expert ultrasound systems using convex and intracavitary transducers. Results. Early amnion integrity impairment was detected in 11 pregnant women at 10 -14 weeks’ gestation. At the same time, major malformations were noted in 6 fetuses, while the anatomical structures were intact in five. Follow-up study revealed that three of them had malformations as ABS or lower extremity deformities formed at 5-16 weeks of pregnancy. The bands could be successfully dissected in utero by fetoscopic surgery in two of the five cases of ABS at 18 weeks of gestation. Conclusion. Timely detection and correct interpretation of fetal malformations and developmental anomalies related to the early amnion rupture spectrum of defects make it possible to optimize pregnancy management tactics and, in some cases, to prevent more severe consequences of this pathological condition.

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About the authors

Olga L. Malmberg

Russian Medical Academy of Continuing Professional Education, Ministry of Health of the Russian Federation; MD Group Clinical Hospital

Email: malmberg.olga@gmail.com
M.D., PhD, associate Professor of the Department of ultrasound in the RMAPO, member of the ISUOG-international society of ultrasound doctors in obstetrics and gynecology, Head of the ultrasound diagnostics Group of Companies “Mother and Child” MD GROUP Clinical hospital.

Mark A. Kurtser

N.I. Pirogov Russian National Research Medical University

Email: m.kurtser@mcclinics.ru
academician of the Russian Academy of Sciences, professor, MD, Head of the Department of Obstetrics and Gynecology

Andrey Ye. Bugerenko

M.V. Lomonosov Moscow State University

Email: jeddit@yandex.ru
M.D, PhD, associate Professor of the Department of obstetrics and gynecology, faculty of fundamental medicine

Lexandra V. Zvereva

"Lapino" Clinical Hospital

Email: dr-zvereva@yandex.ru
M.D., PhD, head of the obstetric Department of pregnancy pathology, obstetrician-gynecologist

Daria I. Sukhanova

M.V. Lomonosov Moscow State University

Email: dashenka-sukhanova@yandex.ru
assistant of the Department of obstetrics and gynecology faculty of fundamental medicine

References

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