Obstetric and neonatal outcomes of different management strategies in fetal macrosomia

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Abstract

Fetal macrosomia is important to study given the high incidence of obstetric and neonatal complications. The induction of labor can reduce the incidence of adverse outcomes in complicated pregnancies. However, the effectiveness of labor induction in reducing the incidence of obstetric and neonatal complications in fetal macrosomia remains controversial.

Objective: To investigate obstetric and neonatal outcomes of different management strategies for fetal macrosomia (expectant management versus labor induction).

Materials and methods: This retrospective cohort study analyzed birth outcomes in 626 healthy primiparous women with fetal macrosomia. The patients were divided into a study group (n=334) with labor induction and a control group (n=295) with expectant management. Each group was divided into gestational age subgroups 1, 2, 3, and 4 of 37–38, 39, 40, and 41 weeks, respectively.

Results: The caesarean section rate for induction of labor at 37-39 weeks was not different from that in the expectant management group, whereas it was significantly higher at 40 weeks (p=0.02). However, at 41 weeks, the situation changed, and the rate of caesarean sections was significantly higher in the expectant management group (p=0.04). There were no differences in the rates of vaginal delivery, fetal shoulder dystocia, or perinatal outcomes.

Conclusion: With the development of fetal macrosomia, it is too late to count on the effectiveness of labor induction, which is the traditional approach to preventing complications. Preventing macrosomia and developing other approaches to prevent its adverse consequences are important.

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About the authors

Oleg V. Tysyachnyi

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Author for correspondence.
Email: o_tysyachny@oparina4.ru
ORCID iD: 0000-0001-9282-9817

PhD, Junior Researcher at the 1st Maternity Department

Russian Federation, Moscow

Oleg R. Baev

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: o_baev@oparina4.ru
ORCID iD: 0000-0001-8572-1971

Dr. Med. Sci., Head of the Maternity Department; Professor at the Department of Obstetrics, Gynecology, Perinatology, and Reproductology

Russian Federation, Moscow; Moscow

Andrey A. Chausov

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: a_chausov@oparina4.ru
ORCID iD: 0000-0002-3094-7209

Head of the Information and Analytical Center of the Department of Regional Cooperation and Integration

Russian Federation, Moscow

Irina V. Edilberg

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: i_edilberg@oparina4.ru
ORCID iD: 0000-0003-4194-8730

PhD Student

Russian Federation, Moscow

Asiyat R. Gaidarova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: a_gadzhieva@oparina4.ru
ORCID iD: 0000-0003-1415-3318

PhD Student

Russian Federation, Moscow

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Supplementary files

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2. Figure. Overall caesarean section rate by gestational age

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