Experience of metroplasty in the second trimester in women with incompetent uterine scar

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Background: The pregnancy rate in patients with incompetent uterine scar (isthmocele) ranges between 1/1800 and 1/2216, which makes up 6.1% of all pregnancies with a history of cesarean section. Isthmocele occurs in 70% of pregnant women who previously underwent uterine surgery and presents a high risk of uterine rupture. Metroplasty during pregnancy is a rare type of medical care that requires profound knowledge and experience in this area.

Case report: The article presents a clinical observation of a 33-year-old patient with a uterine scar in her second pregnancy after having a cesarean section 6 years before. The routine ultrasound examination revealed a 28.0×16.0×40.0 mm isthmocele at 19–20 weeks’ gestation, clinical symptoms were absent. After the patient was hospitalized, metroplasty was performed. The pregnancy was prolonged to 34 weeks due to the administered medications for the prevention of preterm birth. The thickness of the myometrium in the area of the scar was 2.0 mm. When there were complaints indicating the threat of the uterine rupture (pain in the lower abdomen, a decrease in the thickness of the myometrium to 1.8 mm), a cesarean section was performed. A live premature female infant was born weighing 1922 g, 47 cm long, with an Apgar score of 7–8 points. The wound on the uterus was closed with a double-row continuous polyglycolide suture, peritonization was not performed. The postoperative period was uneventful. The patient was discharged on the 3rd day after the operation. After 6 months, the ultrasound examination showed that the endometrium corresponded to the first phase of the cycle, the uterine scar along the anterior wall had no signs of incompetence and was more than 10 mm thick. The child’s development was age-appropriate.

Conclusion: Metroplasty for the incompetent uterine scar is a method of choice that makes possible to prolong a pregnancy and deliver a viable child at the time close to full-term.

Full Text

Restricted Access

About the authors

Anton A. Sukhanov

Perinatal Medical Center; Tyumen State Medical University, Ministry of Health of Russia

Author for correspondence.
Email: such-anton@yandex.ru
ORCID iD: 0000-0001-9092-9136

PhD, Head of the Department of Gynecology, Perinatal Center; Associate Professor, Department of Obstetrics and Gynecology, Institute of Maternity and Childhood, Tyumen State Medical University, Ministry of Health of Russia

Russian Federation, Tyumen; Tyumen

Tatyana V. Legalova

Perinatal Medical Center

Email: such-anton@yandex.ru

PhD, Deputy Chief Physician for Medical Part

Russian Federation, Tyumen

Mikhail A. Obryadov

Tyumen State Medical University, Ministry of Health of Russia

Email: such-anton@yandex.ru
ORCID iD: 0009-0009-8518-1800

student of the Pediatric Faculty

Russian Federation, Tyumen

Galina B. Dikke

F.I. Inozemtsev Academy of Medical Education

Email: galadikke@yandex.ru
ORCID iD: 0000-0001-9524-8962

Dr. Med. Sci., Professor, Department of Obstetrics and Gynecology with a Course of Reproductive Medicine

Russian Federation, St. Petersburg

Irina I. Kukarskaya

Perinatal Medical Center; Tyumen State Medical University, Ministry of Health of Russia

Email: such-anton@yandex.ru
ORCID iD: 0000-0002-8275-3553

Dr. Med. Sci., Associate Professor, Head of the Department of Obstetrics, Gynecology and Perinatology, Institute of Maternity and Childhood, Tyumen State Medical University, Ministry of Health of Russia; Chief Physician, Perinatal Center; Chief Specialist in Obstetrics and Gynecology, Department of Health of the Tyumen Region

Russian Federation, Tyumen; Tyumen

References

  1. WHO. Caesarean section rates continue to rise, amid growing inequalities in access. 16 June 2021.Available at: https://www.who.int/news/
  2. Министерство здравоохранения Российской Федерации, Департамент мониторинга, анализа и стратегического развития здравоохранения, ФГБУ «Центральный научно-исследовательский институт организации и информатизации здравоохранения» Минздрава Российской Федерации. Основные показатели здоровья матери и ребенка, деятельность службы охраны детства и родовспоможения в Российской Федерации. М.; 2020. 169с. [Ministry of Health of the Russian Federation, Department of monitoring, analysis and strategic development of health care, Federal State Budgetary Institution "Central Research Institute for the Organization and Informatization of Healthcare" of the Ministry of Health of the Russian Federation. The main indicators of maternal and child health, the activities of the child protection and obstetric services in the Russian Federation. Moscow; 2020. 169p. (in Russian)].
  3. Biler A., Ekin A., Ozcan A., Inan A.H., Vural T., Toz E. Is it safe to have multiple repeat cesarean sections? A high-volume tertiary care center experience. Pak. J. Med. Sci. 2017; 33(5): 1074-9. https://dx.doi.org/10.12669/pjms.335.12899.
  4. Asghar A., Habib S., Naeem N., Hussain H., Nawaz S., Zafar M. Frequency of cesarean section in patients with previous one scar. P J M H S. 2022; 16(9): 323. https:// dx.doi.org/10.53350/pjmhs22169323.
  5. Жаркин Н.А., Прохватилов С.А., Бурова Н.А., Гаврильчук Т.К., Грамматикова О.А., Мудрая Е.В., Снигур Г.Л. Хирургическая реконструкция рубца на матке во время беременности. Показания, условия и риски. Акушерство и гинекология. 2018; 10: 142-7. [Zharkin N.A., Prokhvatilov S.A., Burova N.A., Gavrilchuk T.K., Grammatikova O.A., Mudraya E.V., Snigur G.L. Surgical reconstruction of the scar on the uterus during pregnancy. Indications, conditions and risks. Obstetrics and Gynecology. 2018; (10): 142-7. (in Russian)]. https:// dx.doi.org/10.18565/ aig.2018.10.142-147.
  6. Глухов Е., Буянова С., Логутова Л., Щукина Н., Дикке Г., ред. Несостоятельный рубец на матке. М.: ГЭОТАР-Медиа; 2020. 288с. [Glukhov E., Buyanova S., Logutova L., Shchukina N., Dicke G., eds. An inconsistent scar on the uterus. Moscow: GEOTAR-Media; 2020. 288p. (in Russian)].
  7. Логинова Е.А., Пономарева Ю.Н., Давыдова И.Ю., Иванова Л.Б., Валиев Р.К. Робот-ассистированная метропластика. Акушерство и гинекология. 2022; 3: 129-37. [Loginova E.A., Ponomareva Yu.N., Davydova I.Yu., Ivanova L.B., Valiev R.K. Robot-assisted metroplasty. Obstetrics and Gynecology. 2022; (3): 129-37. (in Russian)]. https://dx.doi.org/10.18565/aig.2022.3.129-137.
  8. Vervoort A., van der Voet L.F., Hehenkamp W., Thurkow A.L., van Kesteren P., Quartero H. et al. Hysteroscopic resection of a uterine caesarean scar defect (niche) in women with postmenstrual spotting: a randomised controlled trial. BJOG. 2018; 125(3): 326-34. https://dx.doi.org/10.1111/1471-0528.14733.
  9. de Albornoz V.C.A., Carrasco L.I., Pastor M.N., Blanco M.C., Matos M.M., Pacheco A.L., Bartolomé M.E. Outcomes after hysteroscopic treatment of symptomatic isthmoceles in patients with abnormal uterine bleeding and pelvic pain: a prospective case series. Int. J. Fertil. Steril. 2019; 13(2): 108-12. https://dx.doi.org/10.22074/ijfs.2019.5704.
  10. Timor-Tritsch I., Buca D., Di Mascio D., Cali G., D'Amico A., Monteagudo A. et al. Outcome of cesarean scar pregnancy according to gestational age at diagnosis: A systematic review and meta-analysis. Eur. J. Obstet. Gynecol. Reprod. Biol. 2021; 258: 53-9. https://dx.doi.org/10.1016/j.ejogrb.2020.11.036.
  11. Kulshrestha V., Agarwal N., Kachhawa G. Post-caesarean niche (isthmocele) in uterine scar: an update. J. Obstet. Gynaecol. India. 2020; 70(6): 440-6. https://dx.doi.org/10.1007/s13224-020-01370-0.
  12. Савельева Г.М., Курцер М.А., Бреслав И.Ю., Караганова Е.Я., Неклюдова Ю.В. Непроникающий разрыв матки по рубцу после кесарева сечения и расползание/аневризма рубца на матке во второй половине беременности и в родах. Акушерство и гинекология. 2021; 6: 66-72. [Savelyeva G.M., Kurtser M.A., Breslav I.Yu., Karaganova E.Ya., Neklyudova Yu.V. Non-penetrating rupture of the uterus along the scar after caesarean section and spreading/aneurysm of the scar on the uterus in the second half of pregnancy and childbirth. Obstetrics and Gynecology. 2021; (6): 66-72. (in Russian)]. https:// dx.doi.org/10.18565/aig.2021.6.66-72.
  13. Савина Л.В., Ящук А.Г., Гурова З.Г., Архипов В.В., Савин А.М., Масленников А.В. Пролонгирование беременности при расползании рубца на матке после кесарева сечения. Акушерство и гинекология. 2022; 3: 148-54. [Savina L.V., Yashchuk A.G., Gurova Z.G., Arkhipov V.V., Savin A.M., Maslennikov A.V. Prolongation of pregnancy with the spreading of the scar on the uterus after cesarean section. Obstetrics and Gynecology. 2022; (3): 148-54. (in Russian)]. https://dx.doi.org/10.18565/aig.2022.3.148-154.
  14. Maheux-Lacroix S., Li F., Bujold E., Nesbitt-Hawes E., Deans R., Abbott J. Cesarean scar pregnancies: a systematic review of treatment options. J. Minim. Invasive Gynecol. 2017; 24(6): 915-25. https://dx.doi.org/10.1016/ j.jmig.2017.05.019.
  15. Tandukar A., Aryal R., Khaniya B., Maskey S., Ojha N., Chataut D. Pregnancy in an isthmocele: a rare case from Nepal. Clin. Case Rep. 2023; 11(1): e6875. 10.1002/ccr3.6875' target='_blank'>https://dx.doi: 10.1002/ccr3.6875.
  16. Rotas M.A., Haberman S., Levgur M. Cesarean scar ectopic pregnancies: etiology, diagnosis, and management. Obstet. Gynecol. 2006; 107(6): 1373-81. https://dx.doi.org/10.1097/01.AOG.0000218690.24494.ce.
  17. Ben Nagi J., Helmy S., Ofili-Yebovi D., Yazbek J., Sawyer E., Jurkovic D. Reproductive outcomes of women with a previous history of caesarean scar ectopic pregnancies. Hum. Reprod. 2007; 22(7): 2012-5. https://dx.doi.org/10.1093/humrep/dem078.
  18. Pirtea L., Balint O., Secoşan C., Grigoraş D., Pirtea P. Case report: laparoscopic isthmocele repair on an 8 weeks pregnant uterus. Front. Med. (Lausanne). 2022; 9: 831588. https://dx.doi.org/10.3389/fmed.2022.831588.

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. 1. Patient K., 33 y. Pregnancy of 19-20 weeks. Ultrasound examination. Description is given in the text. The fetal head is adjacent to the isthmocele (arrow). Photo from the archive of A. A. Sukhanov

Download (708KB)
3. Fig. 2. Patient K., 33 y. Pregnancy of 19-20 weeks. Laparotomy. Istmocele on the anterior uterine wall (arrows). Photo from the archive of A.A. Sukhanov

Download (893KB)
4. Fig. 3. Patient K., 33 y. Pregnancy of 19-20 weeks. Laparotomy. The result of metroplasty - double-row suture in the area of the isthmocele (arrow). Photo from the archive of A.A. Sukhanov

Download (784KB)

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies