Results of using a combined method of cervical preparation for childbirth
- Authors: Brega Y.S.1, Sakharova G.K.1, Pekarev O.G.1
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Affiliations:
- Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
- Issue: No 11 (2017)
- Pages: 37-43
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248061
- DOI: https://doi.org/10.18565/aig.2017.11.37-43
- ID: 248061
Cite item
Abstract
Objective. To optimize approaches to preparing the cervix uteri for childbirth in patients with the maternal passages being unprepared for labor. To comparatively evaluate the efficiency of a combined method for cervical preparation for childbirth with DILAPAN-S in combination with mifepristone, that of mechanical methods for cervical preparation with DILAPAN-S and a Foley catheter, as well as medical preparation of the cervix with prostaglandin E/PGE). Subjects and methods. The prospective comparative study enrolled 158 pregnant women aged 23 to 38 years (259-284 days of pregnancy). DILAPAN-S 4 was inserted for up to 12 hours in combination with mifepristone 200 mg twice at a 24-hour interval to prepare the cervix uteri for childbirth in 28 women (Group 1); the cervix uteri was prepared for childbirth, by inserting four DILAPAN-S dilators in 30 patients (Group 2); this was carried out, by inserting the balloon of a Foley catheter into the cervix for up to 12 hours in 50 patients (Group 3); the soft maternal passages were prepared for childbirth, by administering PGE2 gel 0.5 mg twice at a 6-hour interval in 50patients (Group 4). Results. The DILAPAN-S + mifepristone group displayed a mean Bishop score of 1.5, 2.14, and 1.9 higher than in the DILAPAN-S, Foley catheter, and PGE2 gel groups, respectively. In addition, the proportion of vaginal births was significantly higher in Group 1 than in the Foley catheter and PGE2 gel groups. The duration of labor differed in Groups 1-3, 2-3, and 3-4. Additional labor preinduction and induction were needed only in Groups 2, 3, and 4. Conclusion. The combined method of cervical preparation for childbirth with DILAPAN-S in combination with mifepristone of 200 mg twice is a more effective method than mechanical techniques, such as DILAPAN-S, a Foley catheter or medical preparation of the cervix with PGE2 gel.
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About the authors
Yevgeny S. Brega
Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: e_brega@oparina4.ru
obstetrician-gynecologist
Galina K. Sakharova
Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: g_sakharova@oparina4.ru
Clinical resident
Oleg Grigorievich Pekarev
Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: o_pekarev@oparina4.ru
MD, professor, deputy chief physician
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