DETERMINATION OF FREE EMBRYONIC DNA IN THE PLASMA OF PREGNANT WOMEN FOR NONINVASIVE PRENATAL GENETIC DIAGNOSIS
- Авторлар: TETRUASHVILI N.K1, FEDOROVA N.I1, FAIZULLIN L.Z1, KARNAUKHOV V.N1
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Мекемелер:
- Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
- Шығарылым: № 6 (2012)
- Беттер: 4-8
- Бөлім: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246776
- ID: 246776
Дәйексөз келтіру
Аннотация
The need for timely diagnosis with the minimum risk to mother and fetus determines whether it is urgent to make a noninvasive prenatal diagnosis. The detection of free (extracellular) embryonic DNA circulating in the maternal plasma has opened up fresh opportunities for the noninvasive genetic diagnosis of the fetus and the state of pregnancy. Embryonic DNA may be detected at 5—6 weeks’ gestation and promptly disappears after childbirth. Current molecular biological technologies to investigate this DNA make it possible to predict pregnancy complications, to define fetal sex and rhesus, and to diagnose gene and chromosomal mutations.
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Авторлар туралы
N. TETRUASHVILI
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
Email: tetrauly@mail.ru
N. FEDOROVA
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
Email: natasha_fedorova@mail.ru
L. FAIZULLIN
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
Email: lfaizullin@mail.ru
V. KARNAUKHOV
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
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