Reproductive disorders in female patients with respiratory organ tuberculosis


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Objective: to study the specif ic features of reproductive disorders in female patients with active respiratory organ tuberculosis (ROT) during their stay at specialized hospital. Subjects and methods. Two hundred and sixty-eight women: 1) 142 patients with active ROT (a study group); 2) 126 healthy women (a control group) were examined. General and specialized studies (collection of history data; examination; analysis of respiratory organ X-ray tomographic findings; clinical and biochemical analyses of blood; coagulogram; microbiological and molecular genetic examinations of sputum and menstrual blood; examination of the level of female sex hormones; cytological and molecular genetic studies of vaginal discharge) were performed. Results. 44.4% of the patients with ROT were found to have menstruation irregularities; 64.1% had genital mucosal biocenotic changes that clinically showed themselves as recurrent inflammatory diseases; the rate of cervical abnormalities was 49.3%. 54.9% had inflammatory diseases of the internal genitalia, which were characterized by an acute course and possible lympho- and hematogenous dissemination of tuberculosis infection, which permit them to be assigned to a group at risk for genital tuberculosis. Conclusion. The timely, rationally chosen chemotherapy and the diagnosis and treatment of reproductive disorders decrease the probable dissemination of tuberculosis infection and the development of genital tuberculosis, promote the prevention of cancer of the cervix uteri, improve reproductive health, and increase the future reproductive potential.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Svetlana Kayukova

Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences

Email: kajukovalnp@gmail.com
Candidate of Medical Sciences, Senior Researcher, Clinical and Diagnostic Department

Elena Uvarova

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: elena-uvarova@yandex.ru
MD, Professor, Head of the 2nd gynecological department

Olga Demikhova

Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences

Email: demikhova@mail.ru
MD, professor, deputy for the Director

Atajan Ergeshov

Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences

Email: cniit@ramn.ru
MD, professor, deputy for the Director

Әдебиет тізімі

  1. Нечаева О.Б. Мониторинг и оценка изменений эпидемиологических показателей по туберкулезу в Российской Федерации. Туберкулез и болезни легких. 2012; 8: 16-22. [Nechaeva O.B. Monitoring and evaluation of changes in epidemiological indicators of TB in the Russian Federation. Tuberkulez i bolezni legkih. 2012; 8: 16-22. (in Russian)]
  2. Ситуация по туберкулезу и работе противотуберкулезной службы РФ в 2012г. Материалы Федерального Центра мониторинга противодействия распространению туберкулеза. Центральный НИИ организации и информатизации здравоохранения. М.; 2013. Available at: http:// www.mednet.ru/images/stories/files/CMT/2012_ tvs_rossiya.pdf [The tuberculosis situation and the work of the TB service of the Russian Federation in 2012. Proceedings of the Federal Centre for Monitoring counter the spread of tuberculosis. Central Research Institute of organization and informatization of Healthcare. M.; 2013. (in Russian)]
  3. Ghosh K., Chowdhury J.R. Tuberculosis and female reproductive health. J. Postgrad. Med. 2011; 57(4): 307-13.
  4. Samaila M.O., Adesiyun A.G., Mohammed T.T., Adewuyi S.A., Usman B. Tuberculosis of the female breast and reproductive organs: a diagnostic dilemma. J. Trop. Dis. 2013; 1(3): 116. doi: 10.4172/2329-891X.1000116.
  5. Kumar R. Reproductive tract tuberculosis and male infertility. Indian J. Urol. 2008; 24(3): 392-5.
  6. Hassan W.A., Darwish A.M. Impact of pulmonary tuberculosis on menstrual pattern and fertility. Chest. 2009; 136(1): 326-31.

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