The indicators of acid-base balance and the gas composition of umbilical cord arterial and venous blood in health and fetal hypoxia
- Авторлар: Prikhodko A.M.1, Romanov A.Y.1, Shuklina D.A.1, Baev O.R.2,3
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Мекемелер:
- National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation
- National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia
- I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
- Шығарылым: № 2 (2019)
- Беттер: 93-97
- Бөлім: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248441
- DOI: https://doi.org/10.18565/aig.2019.2.93-97
- ID: 248441
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Аннотация
Objective. To compare the indicators of acid-base balance in the neonatal umbilical cord artery and vein in health and fetal hypoxia. Material and methods. A prospective observational study was performed using 98 umbilical cord blood samples. Results. The pH value was lower in the umbilical artery (7.252 ± 0.100 than that in the umbilical vein (7.297 ± 0.097) (p < 0.0001). The lactate level did not differ and was 5.929±2.807 mmol/l in the umbilical artery and 5.661 ± 2.898 mmol/l in the umbilical vein (p = 0.1074). The partial pressure of carbon dioxide was predictably higher in the umbilical artery (47.56 ± 12.68 mm Hg) than that in the umbilical vein (39.69 ± 9.70 mm Hg) (p < 0.0001); the partial pressure of oxygen was higher in the umbilical vein (17.56 ± 6.134 mm Hg) than that in the umbilical artery (23.36 ± 10. 09 mm Hg) (p < 0.0001). Conclusion. When pH values are determined, the source of umbilical cord blood sampling is critically important, whereas when lactate levels are measured, any umbilical vessel may be used. It is important to take into account the found patterns in clinical practice.
Негізгі сөздер
Толық мәтін
Авторлар туралы
Andrey Prikhodko
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation
Email: a_prikhodko@oparina4.ru
PhD, physician of the maternity department
Andrey Romanov
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation
Email: romanov1553@yandex.ru
clinical resident
Daria Shuklina
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation
Email: shuk2323@mail.ru
clinical resident
Oleg Baev
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Email: metod_obsgyn@hotmail.com
MD, professor, head of the first Maternity Department; Department of Obstetrics, Gynecology, Perinatology and Reproduction.
Әдебиет тізімі
- Simovic A., Stojkovic A., Savic D., Milovanovic D.R. Can a single lactate value predict adverse outcome in critically ill newborn? Bratisl. Lek. Listy. 2015; 116(10): 591-5.
- Ozkiraz S., Gokmen Z., Boke S.B., Kilicdag H., Ozel D., Sert A. Lactate and lactate dehydrogenase in predicting the severity of transient tachypnea of the newborn. J. Matern. Fetal Neonatal Med. 2013; 26(12):1245-8.
- Приходько А.М., Киртбая А.Р., Романов А.Ю., Баев О.Р. Биомаркеры повреждения головного мозга у новорожденных. Неонатология. 2018; 7(1): 70-6.
- Fine-Goulden M.R., Durward A. How to use lactate. Arch. Dis. Child. Educ. Pract. Ed. 2014; 99(1): 17-22.
- Приходько А.М., Романов А.Ю., Евграфова А.В., Шуклина Д.А. Определение уровня pH и лактата крови из предлежащей части плода для оценки его состояния в родах. Вопросы гинекологии, акушерства и перинатологии. 2017; 16(6): 96-9.
- Приходько А.М., Баев О.Р. Определение кислотно-основного состояния пуповинной крови. Показания и техника. Акушерство и гинекология. 2018; 5:127-31.
- Kruse O., Grunnet N., Barfod C. Blood lactate as a predictor for in-hospital mortality in patients admitted acutely to hospital: a systematic review. Scand. J. Trauma Resusc. Emerg. Med. 2011; 19: 74.
- Araujo O.R., Diegues A.R., Silva D.C., Albertoni Ade C., Louzada M.E., Cabral E.A. et al. Agreement and correlation of pH, bicarbonate, base excess and lactate mea surements in venous and arterial blood of premature and term infants. Rev. Bras. Ter Intensiva. 2007; 19(3): 322-6.
- Nadeem M., Clarke A, Dempsey E.M. Day 1 serum lactate values in preterm infants less than 32 weeks gestation. Eur. J. Pediatr. 2010; 169(6): 667-70.
- Buijs E.A., Houmes R.J., Rizopoulos D., Wildschut E.D., Reiss I.K., Ince C. et al. Arterial lactate for predicting mortality in children requiring extracorporeal membrane oxygenation. Minerva Anestesiol. 2014; 80(12): 1282-93.
- Maisonneuve E., Audibert F., Guilbaud L., Lathelize J., Jousse M., Pierre F. et al. Risk factors for severe neonatal acidosis. Obstet. Gynecol. 2011; 118(4): 818-23.
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