Assessment of the informative value of a regional cervical screening program

To assess the results of using a careHPV test kit as a quick screening test in the organized cervical cancer (CC) screening program in the Republic of Ingushetia. Human papillomavirus (HPV) testing was carried out in 1000 women aged 30 to 60 years to identify 14 high-risk HPV types, by using the hybrid capture assay. High-risk HPV was detected in 107 (10.7%) women. All the women (n = 107) were referred to visual inspection with acetic acid; and 81 (75.7%) women of them underwent a cytological examination of cervical smears for suspected dysplasia. Fifteen (1.5%) women with cytologically verified CIN II-III were sent to the Republican Oncology Dispensary for cervical excision with histological examination of biopsy specimens.Taking into account that HPV infection is a major etiological factor for the pathogenesis of CC, in order to reduce its morbidity and mortality, it is recommended that HPV testing should be introduced into the algorithm of the organizational form of early CC diagnosis among the republic’s female population aged 30 to 60 years.

human papillomavirus, cervical cancer, screening, Republic of Ingushetia