RELATIONSHIP OF PATHOZOOSPERMIA AND CHROMOSOME ANEUPLOIDY IN THE SPERM AND EMBRYOS IN ASSISTED REPRODUCTIVE TECHNOLOGY PROGRAMS


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Resumo

This review estimates the incidence of aneuploidy in the sperm nuclei and embryos of males with reproductive dysfunction and fertility. It gives the data of studies evaluating the impact of different types of pathozoospermia on the level of chromosome aneuploidy in the sperm nuclei. Chromosome aneuploidy in the sperm was assessed for its influence on that in the embryos. The outcomes of assisted reproductive technology programs were analyzed in the married couples in which the husbands had elevated sperm chromosome aneuploidy. The possibilities of using preimplantation genetic diagnosis as a measure to prevent the birth of babies with genetic pathology in this category of patients are considered.

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Sobre autores

S. SOKUR

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: sokursv@yandex.ru

N. DOLGUSHINA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: n_dolgushina@oparina4.ru

ZH. GLINKINA

OOO "Petrovskie Vorota" Maternity and Reproductive Medicine Center

Email: z_glinkina@oparina4.ru

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