Polycystic ovary syndrome in adolescents suffering from excessive body weight and insulin resistance
- Autores: Khashchenko E.P.1, Vysokikh M.Y.1,2, Batyrova Z.K.1, Kumykova Z.K.1, Uvarova E.V.1, Ivanetc T.Y.1, Tsvirkun D.V.1, Vtorushina V.V.1
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Afiliações:
- FSBI "National Medical Research Center for Obstetrics, Gynecology and Perinatology "of the Ministry of Healthcare of the Russian Federation
- A.N. Belozersky Research Institute of Physicochemical Biology
- Edição: Nº 12 (2018)
- Páginas: 94-102
- Seção: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248344
- DOI: https://doi.org/10.18565/aig.2018.12.94-102
- ID: 248344
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Sobre autores
Elena Khashchenko
FSBI "National Medical Research Center for Obstetrics, Gynecology and Perinatology "of the Ministry of Healthcare of the Russian Federation
Email: khashchenko_elena@mail.ru
PhD, researcher at the Department of Pediatric Gynecology
Mikhail Vysokikh
FSBI "National Medical Research Center for Obstetrics, Gynecology and Perinatology "of the Ministry of Healthcare of the Russian Federation; A.N. Belozersky Research Institute of Physicochemical Biology
Email: m_vysokikh@oparina4.ru
PhD, Head of mitochondrial medicine research group; Head of aging molecular mechanism group
Zalina Batyrova
FSBI "National Medical Research Center for Obstetrics, Gynecology and Perinatology "of the Ministry of Healthcare of the Russian Federation
Email: linadoctor@mail.ru
PhD, researcher at the Department of Pediatric Gynecology
Zaira Kumykova
FSBI "National Medical Research Center for Obstetrics, Gynecology and Perinatology "of the Ministry of Healthcare of the Russian Federation
Email: zai-kumykova@yandex.ru
PhD, senior researcher at the Department of Pediatric Gynecology
Elena Uvarova
FSBI "National Medical Research Center for Obstetrics, Gynecology and Perinatology "of the Ministry of Healthcare of the Russian Federation
Email: elena-uvarova@yandex.ru
MD, PhD, Professor, Head of the Department of pediatric and adolescent gynecology
Tatyana Ivanetc
FSBI "National Medical Research Center for Obstetrics, Gynecology and Perinatology "of the Ministry of Healthcare of the Russian Federation
Email: t_ivanets@oparina4.ru
PhD, MD, Head of the Department of Research and Diagnostics Laboratory
Darya Tsvirkun
FSBI "National Medical Research Center for Obstetrics, Gynecology and Perinatology "of the Ministry of Healthcare of the Russian Federation
Email: darunyat@gmail.com
PhD, researcher at mitochondrial medicine research group
Valentina Vtorushina
FSBI "National Medical Research Center for Obstetrics, Gynecology and Perinatology "of the Ministry of Healthcare of the Russian Federation
Email: v_vtorushina@oparina4.ru
PhD, clinician of laboratory diagnostics at the department of clinical immunology
Bibliografia
- Deligeoroglou E., Vrachnis N., Athanasopoulos N., Iliodromiti Z., Sifakis S., Iliodromiti S. et al. Mediators of chronic inflammation in polycystic ovarian syndrome. Gynecol. Endocrinol. 2012; 28(12): 974-8. doi: 10.3109/09513590.2012.683082.
- Чернуха Г.E., Блинова И.В., Купрашвили М.И. Эндокринно-метаболические характеристики больных с различными фенотипами синдрома поликистозных яичников. Акушерство и гинекология. 2011; 2: 70-6.
- El Hayek S., Bitar L., Hamdar L.H., Mirzfl E.G., Daoud G. Poly cystic ovarian syndrome: an updated overview. Front. Physiol. 2016; 7: 124. doi: 10.3389/ fphys.2016.00124.
- Rojas J., Chavez М., Olivar L., Rojas М., Morillo J., Mejias J. Polycystic ovary syndrome, insulin resistance, and obesity: navigating the patophysiologic labyrinth. Int. J. Reprod. Med. 2014; 2014: 719050. doi: 10.1155/2014/719050.
- De Sousa S.М., Norman R.J. Metabolic syndrome, diet and exercise. Best Pract. Res. Clin. Obstet. Gynaecol. 2016; 37: 140-51. doi: 10.1016/j.bpobgyn.2016.01.006.
- Goodman N.F., Cobin R.H., Eutterweit W., Glueck J.S., Legro R.S., Carmina E. American association of clinical endocrinologists, american college of endocrinology, and androgen excess and pcos society disease state clinical review: guide to the best practices in the evaluation and treatment of polycystic ovary syndrome- part 1. Endocr. Pract. 2015; 21(11): 1291-300. doi: 10.4158/EP15748.DSC.
- Oleszczak B., Szflblewski L., Pliszka М., Gluszak O., Stopinska-Gluszak U. Transport of deoxy-d-glucose into lymphocytes of patients with polycystic ovary syndrome. Endocrine. 2014; 47(2): 618-24. doi: 10.1007/sl2020-014-0174-5.
- Dumesic D.A., Oberfield S.E., Stener-Victorin E., Marshall J.C., Laven J.S., Legro R.S. Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome. Endocr. Rev. 2015; 36(5): 487-525. doi: 10.1210/er.2015-1018.
- Diamanti-Kandarakis E., Dunaif A. Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocr. Rev. 2012; 33(6): 981-1030.
- Gonzfllez E. Inflammation in polycystic ovary syndrome: underpinning of insulin resistance and ovarian dysfunction. Steroids. 2012; 77(4): 300-5. doi: 10.1016/j.steroids.2011.12.003.
- Yang Y., Qiao J., Li R., Li M.Z. Is interleukin-18 associated with polycystic ovary syndrome? Reprod. Biol. Endocrinol. 2011; 9: 7-18. doi: 10.1186/1477-7827-9-7.
- Tao Т., Li S., Zhao A., Zhang Y., Liu W. Expression of the CDllc gene in subcutaneous adipose tissue is associated with cytokine level and insulin resistance in women with polycystic ovary syndrome. Eur. J. Endocrinol. 2012; 167(5): 705-13. doi: 10.1530/EJE-12-0340.
- Escobar-Morreale H.F., Luque-Ramirez М., Gonzfllez, F. Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and meta-analysis. Fertil. Steril. 2011; 95(3): 1048-58. doi: 10.1016/j.fertnstert.2010.11.036.
- Lee H., Oh J.Y., Sung Y.A. Adipokines, insulin-like growth factor binding protein-3 levels, and insulin sensitivity in women with polycystic ovary syndrome. Korean J. Intern. Med. 2013; 28(4): 456-63. doi: 10.3904/kjim.2013.28.4.456.
- Conway G., Dewailly D., Diamanti-Kandarakis E., Escobar-Morreale H.F., Franks S., Gambineri A. et al. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur. J. Endocrinol. 2014; 171: 1-29. doi: 10.1530/EJE-14-0253.
- Amato М. C. Metabolically healthy polycystic ovary syndrome (MH-PCOS) and metabolically unhealthy polycystic ovary syndrome (MU-PCOS): a comparative analysis of four simple methods useful for metabolic assessment. Hum. Reprod. 2013; 28(7): 1919-28.
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