The expression profile of placental microRNAs as regulators of oxidative stress in fetal growth restriction
- Autores: Gusar V.A.1, Timofeeva A.V.1, Kan N.E.1, Chagovets V.V.1, Ganichkina M.B.1, Frankevich V.E.1
-
Afiliações:
- National Medical Research Center for Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russian Federation
- Edição: Nº 1 (2019)
- Páginas: 74-80
- Seção: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248434
- DOI: https://doi.org/10.18565/aig.2019.L74-80
- ID: 248434
Citar
Texto integral
![Acesso aberto](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_open.png)
![Acesso é fechado](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_unlock.png)
![Acesso é fechado](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_lock.png)
Resumo
Texto integral
![Acesso é fechado](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_lock.png)
Sobre autores
Vladyslava Gusar
National Medical Research Center for Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russian Federation
Email: v_gusar@oparina4.ru
PhD, senior researcher of Laboratory of Applied Transriptomics, Department of System Biology in Reproduction
Angelika Timofeeva
National Medical Research Center for Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russian Federation
Email: v_timofeeva@oparina4.ru
PhD, senior researcher of Laboratory of Applied Transriptomics, Department of System Biology in Reproduction
Natalia Kan
National Medical Research Center for Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russian Federation
Email: n_kan@oparina4.ru
MD, professor, head of Department of Obstetric Observatory
Vitaliy Chagovets
National Medical Research Center for Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russian Federation
Email: v_chagovets@oparina4.ru
PhD, senior researcher of Laboratory of Proteomics and Metabolomics of Human Reproduction, Department of Systems Biology in Reproduction
Maria Ganichkina
National Medical Research Center for Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russian Federation
Email: m_ganichkina@oparina4.ru
graduate student
Vladimir Frankevich
National Medical Research Center for Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russian Federation
Email: v_frankevich@oparina4.ru
PhD, head of Department of Systems Biology in Reproduction
Bibliografia
- Devaskar S. U., Chu A. Intrauterine growth restriction: hungry for an answer. Physiology (Bethesda). 2016; 31(2): 131-46. https://dx.doi.org/10.1152/ physiol.00033.2015.
- Audette M.C., Kingdom J.C. Screening for fetal growth restriction and placental insufficiency. Semin. Fetal Neonatal Med. 2018; 23(2): 119-25. https://dx.doi. org/10.1016/j.siny.2017.11.004.
- Miller S.L., Huppi P.S., Mallard C. The consequences of fetal growth restriction on brain structure and neurodevelopmental outcome. J. Physiol. 2016; 594(4): 807-23. https://dx.doi.org/.1113/JP271402.
- Schools M.H., Gordijn S.J., Scherjon S.A., van Goor H., Hillebrands J.L. Oxidative stress in placental pathology. Placenta. 2018; 69: 153-61. https:// dx.doi.org/10.1016/ j.placenta.2018.03.003.
- Myatt L., Cui X. Oxidative stress in the placenta. Histochem. Cell Biol. 2004; 122(4): 369-82. https://dx.doi.org/10.1007/s00418-004-0677-x.
- Higashijima A., Miura K., Mishima H., Kinoshita A., Jo O., Abe S. et al. Characterization of placenta-specific microRNAs in fetal growth restriction pregnancy. Prenat. Diagn. 2013; 33(3): 214-22.
- Rudov A., Balduini W., Carloni S., Perrone S., Buonocore G., Cristina M. Involvement of miRNAs in placental alterations mediated by oxidative stress. Oxid. Med. Cell. Longev. 2014; 2014: 103068. https://dx.doi. org/10.1155/2014/103068.
- Magenta A., Greco S., Gaetano C., Martelli F. Oxidative stress and microRNA in vascular diseases. Int. J. Mol. Sci. 2013; 14(9): 17319-46.
- Cicchillitti L., Di Stefano V., Isaia E., Crimaldi L., Fasanaro P., Ambrosino V. et al. Hypoxia-inducible factor 1-alpha induces miR-210 in normoxic differentiating myoblasts. J. Biol. Chem. 2012; 287(53): 44761-71.
- Hu Y., Li P., Hao S., Liu L., Zhao J., Hou Y. Differential expression of microRNAs in the placentae of Chinese patients with severe pre-eclampsia. Clin. Chem. Lab. Med. 2009; 47(8): 923-9.
- Cross C.E., Tolba M.F., Rondelli C.M., Xu M., Abdel-Rahman S.Z. Oxidative stress alters miRNA and gene expression profiles in villous first trimester trophoblasts. Biomed. Res. Int. 2015; 2015: 257090. https://dx.doi.org/10.1155/2015/257090.
- Team R.C. R: A language and environment for statistical computing. R foundation for statistical computing, Vienna, Austria, 2017. Available at: https:// www.R-project.org/
- Hromadnikova I., Kotlabova K., Hympanova L., Krofta L. Cardiovascular and cerebrovascular disease associated microRNAs are dysregulated in placental tissues affected with gestational hypertension, preeclampsia and intrauterine growth restriction. PLoS One.| 2015; 10(9): e0138383. https://dx.doi. org/10.1371/journal.pone.0138383.
- Hromadnikova I., Kotlabova K., Ivankova K., Vedmetskaya Yu., Krofta L. Profiling of cardiovascular and cerebrovascular disease associated microRNA expression in umbilical cord blood in gestational hypertension, preeclampsia and fetal growth restriction. Int. J. Cardiol. 2017; 249: 402-9. https://dx.doi. org/10.1016/j.ijcard.2017.07.045.
- Hromadnikova I., Kotlabova K., Hympanova L., Krofta L. Gestational hypertension, preeclampsia and intrauterine growth restriction induce dysregulation of cardiovascular and cerebrovascular disease associated microRNAs in maternal whole peripheral blood. Thromb. Res. 2016; 137: 126-40.
- Liu X., Cheng Y., Yang J., Xu L., Zhang C. Cell-specific effects of miR-221/222 in vessels: molecular mechanism and therapeutic application. J. Mol. Cell. Cardiol. 2012; 52(1): 245-55. https://dx.doi.org/ 10.1016/ j.yjmcc.2011.11.008.
- Sladek S.M., Magness R.R., Conrad K.P. Nitric oxide and pregnancy. Am. J. Physiol. 1997; 272(2, Pt 2): R441-63.
- Zhang C., Zhang J., Zhang A., Wang Y., Han L., You Y. et al. PUMA is a novel target of miR-221/222 in human epithelial cancers. Int. J. Oncol. 2010; 37(6): 1621-6.
- Liang Y., Xu J., Wang Y., Tang J.Y., Yang S.L., Xiang H.G. et al. Inhibition of MiRNA-125b decreases cerebral ischemia/reperfusion injury by targeting CK2a/NADPH oxidase signaling. Cell. Physiol. Biochem. 2018; 45(5): 1818-26. https://dx.doi.org/10.1159/000487873.
- Shen Y., Shen Z., Guo L., Zhang Q., Wang Z., Miao L. et al. MiR-125b-5p is involved in oxygen and glucose deprivation injury in PC-12 cells via CBS/ H2S pathway. Nitric Oxide. 2018; 78(1): 11-21. https://dx.doi.org/10.1016/j. niox.2018.05.004.
- Yu Q., Lu Z., Tao L., Yang L., Guo Y., Yang Y. et al. ROS-dependent neuroprotective effects of NaHS in ischemia brain injury involves the PARP/ AIF pathway. Cell. Physiol. Biochem. 2015; 36(4): 1539-51.
- Shah N.M., Zaitseva L., Bowles K.M., MacEwan D.J., Rushworth S.A. NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival. Cell Death Differ. 2015; 22(4): 654-64. https://dx.doi.org/ 10.1038/cdd.2014.152.
- Mert I., Oruc A.S., Yukse S., Cakar E.S., Buyukkagnici U., Karaer A., Danisman N. Role of oxidative stress in preeclampsia and intrauterine growth restriction J. Obstet. Gynaecol. Res. 2012; 38(4): 658-64. https://dx.doi. org/10.1111/j.1447-0756.2011.01771.x.
- Biberoglu E., Biberoglu K., Kirbas A., Daglar K., Genc M., Avci A., Danisman N. Circulating and myometrial markers of oxidative stress in pregnant women with fetal growth restriction. J. Obstet. Gynaecol. Res. 2015; 42(1): 29-35. https:// dx.doi.org/10.1111/jog.12857.
- WangX., Zhu H., Zhang X., Liu Y., Chen J., Medvedovic M. et al. Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1. Cardiovasc. Res. 2012; 94(2): 379-90.
- Yu D., dos Santos C.O., Zhao G., Jiang J., Amigo J.D., Khandros E. et al. MiR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta. Genes Dev. 2010; 24(15): 1620-33.
- Alural B., Duran G.A., Tufekci K.U., Allmer J., Onkal Z., Tunali D. et al. EPO mediates neurotrophic, neuroprotective, anti-oxidant, and anti-apoptotic effects via downregulation of miR-451 and miR-885-5p in SH-SY5Y neuron-like cells. Front. Immunol. 2014; 4: 475. https://dx.doi.org/10.3389/fimmu.2014.00475.
- Bostjancic E., Zidar N., Glavac D. MicroRNAs and cardiac sarcoplasmic reticulum calcium ATPase-2 in human myocardial infarction: expression and bioinformatics analysis. BMC Genomics. 2012; 13(1): 552.
Arquivos suplementares
![](/img/style/loading.gif)