Ultrasound assessment of the effect of chronic endometritis treatment

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Objective: To assess the dynamics of echographic changes in the endometrium in patients receiving complex treatment for chronic endometritis using cytokine therapy.

Materials and methods: This was a retrospective analysis of 298 reproductive-aged women diagnosed with chronic endometritis. The main group consisted of 140 patients who received standard anti-inflammatory treatment supplemented with cytokine therapy. The comparison group included 158 women who were treated with a similar complex but they did not receive cytokine therapy. There was an assessment of the ultrasound parameters which were used for ultrasound diagnosis of chronic endometritis.

Results: After therapy there was a statistically significant decrease (p<0.05) in the thickness and volume of the endometrium, as well as a decrease in the frequency of detection of most ultrasound signs of chronic endometritis. The disappearance of fluid and gas bubbles from the uterine cavity turned out to be the most pronounced effect of the treatment. The echogenicity of the endometrium and its heterogeneous structure did not change much (p>0.05).

Conclusion: The use of cytokine therapy in the complex treatment of chronic endometritis makes it possible to bring the ultrasound criteria closer to the standard parameters; the changes in the criteria indicate the partial restoration of the endometrium.

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Sobre autores

Irina Ozerskaya

Peoples’ Friendship University of Russia (RUDN University)

Autor responsável pela correspondência
Email: ozerskaya_usd@mail.ru
ORCID ID: 0000-0001-8929-6001

Dr. Med. Sci., Professor, Department of Ultrasound Diagnostics

Rússia, Moscow

Gayane Kazaryan

Medscan LLC

Email: 79165521271@yandex.ru
ORCID ID: 0000-0002-1198-8187

PhD, Ultrasound Diagnostics Doctor

Rússia, Moscow

Alexander Gus

Peoples’ Friendship University of Russia (RUDN University); Academician V.I. Kulakov National Medical Research Centre for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: a_gus@oparina4.ru
ORCID ID: 0000-0003-1377-3128

Dr. Med. Sci., Professor, Chief Researcher; Head of the Department of Ultrasound Diagnostics

Rússia, Moscow; Moscow

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