Prediction of placental insufficiency in multiple pregnancy, by identifying placental growth factor
- 作者: Barinov S.V.1, Rogova E.V.1, Kadtsyna T.V.2, Shamina I.V.2
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隶属关系:
- Omsk State Medical Academy
- Omsk State Medical Academy, Ministry of Health of Russia
- 期: 编号 7 (2015)
- 页面: 43-47
- 栏目: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/247478
- ID: 247478
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详细
Objective. To improve perinatal outcomes in multiple pregnancy, by predicting gestational complications and elaborating a package of diagnostic and treatment measures in this group of pregnant women. Subjects and methods. A study group consisted of 124 women having a multiple pregnancy who underwent an elaborated system of diagnostic and treatment measures; a comparison group included 126 women having a multiple pregnancy who underwent the standard examination and treatment procedure. A control group comprised 50 women having a single pregnancy. Resu1ts. Examination of serum placental growth factor (PlGF) levels in 124 women with the first trimester (6-8 weeks) of pregnancy with preeclampsia and multiple pregnancy indicated that very low maternal serum PlGF levels (111.5±8.2 μmol/l) favored the development of decompensated placental insufficiency and early miscarriage (r = 0.89; p < 0.01). Conclusion. Based on these markers for endothelial dysfunction, the authors elaborated and introduced a package of diagnostic and treatment measures, which could improve perinatal outcomes and reduce perinatal losses by 1.5 times (14.4% in 2012 to 9.8% in 2014).
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作者简介
Sergey Barinov
Omsk State Medical Academy
Email: barinov_omsk@mail.ru
M.D., Associate Professor, head of the chair of Obstetrics and Gynecology № 1
Elena Rogova
Omsk State Medical Academy
Email: elena_omsk67@mail.ru
Candidate of Medical Science, Assistant of the chair of Obstetrics and Gynecology № 2
Tatiana Kadtsyna
Omsk State Medical Academy, Ministry of Health of Russia
Email: tatianavlad@list.ru
Candidate of Medical Science, Assistant of the chair of Obstetrics and Gynecology № 2
Inna Shamina
Omsk State Medical Academy, Ministry of Health of Russia
Email: innadocsever@rambler.ru
Candidate of Medical Science, Assistant of the chair of Obstetrics and Gynecology № 2
参考
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