Fluorescence hysteroresectoscopy in the clarifying diagnosis of early endometrial cancer

Objective. To acquaint practitioners with a fluorescence hysteroresectoscopy technique in improving the diagnosis of atypical hyperplasia and early endometrial cancer. Material and methods. The paper describes the fluorescence hysteroresectoscopy technique performed at the Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. Results. Fluorescence hysteroresectoscopy makes it possible to identify the topography of neoplasia and the selectivity of photosensitizer (5-ALA) accumulation in tumor tissue and to perform a targeted biopsy from the maximum fluorescence foci for histological verification. Conclusion. The introduction of fluorescence hysteroresectoscopy in clinical practice will be able to assess the possibility and success of organ-sparing treatment (hormone therapy) in reproductive-aged women, to monitor the endometrial status, and to timely diagnose a recurrence during or after hormone therapy in patients with early endometrial cancer.

early endometrial cancer, fluorescence hysteroresectoscopy, organ-sparing treatment, diagnosis, oncology