Fluorescence hysteroresectoscopy in the clarifying diagnosis of early endometrial cancer


Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Acesso é pago ou somente para assinantes

Resumo

Objective. To acquaint practitioners with a fluorescence hysteroresectoscopy technique in improving the diagnosis of atypical hyperplasia and early endometrial cancer. Material and methods. The paper describes the fluorescence hysteroresectoscopy technique performed at the Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. Results. Fluorescence hysteroresectoscopy makes it possible to identify the topography of neoplasia and the selectivity of photosensitizer (5-ALA) accumulation in tumor tissue and to perform a targeted biopsy from the maximum fluorescence foci for histological verification. Conclusion. The introduction of fluorescence hysteroresectoscopy in clinical practice will be able to assess the possibility and success of organ-sparing treatment (hormone therapy) in reproductive-aged women, to monitor the endometrial status, and to timely diagnose a recurrence during or after hormone therapy in patients with early endometrial cancer.

Texto integral

Acesso é fechado

Sobre autores

Stanislav Pronin

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia

Email: psm_doc@mail.ru
PhD, oncologist, obstetrician-gynecologist, senior Researcher of Department of Innovative Oncology and Gynecology

Irina Matsneva

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: via.white.doc@gmail.com
student of the 6th year medical faculty

Muslim Maltsagov

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia

Email: terekman94@gmail.com
clinical resident of Ith year

Bibliografia

  1. Каприн А.Д., Старинский В.В., Петрова Г.В., ред. Злокачественные новообразования в России в 2016 году (заболеваемость и смертность). М.: МНИОИ им. П.А. Герцена - филиал ФГБУ «НМИЦ радиологии» Минздрава России; 2018.
  2. Edometrial Cancer Treatment (PDQ). National Cancer Institute. 23 April 2014. Archived from the original on 3 September 2014. Retrieved 3 September 2014.
  3. Gunderson C.C., Fader A.N., Carson K.A., Bristow R.E. Oncologic and reproductive outcomes with progestin therapy in women with endometrial hyperplasia and grade 1 adenocarcinoma: a systematic review. Gynecol. Oncol. 2012; 125(2): 477-82.
  4. Gonthier C., Walker F., Luton D., Yazbeck C., Madelenat P., Koskas M. Impact of obesity on the results of fertility-sparing management for atypical hyperplasia and grade 1 endometrial cancer. Gynecol. Oncol. 2014; 133(1): 33-7.
  5. Pal N., Broaddus R.R., Urbauer D.L., Balakrishnan N., Milbourne A., Schmeler K.M. et al. Treatment of low-risk endometrial cancer and complex atypical hyperplasia with the levonorgestrel-releasing intrauterine device. Obstet. Gynecol. 2018; 131(1): 109-16.
  6. Loiacono R.M., Trojano G., Del Gaudio N., Kardhashi A., Deliso M.A., Falco G. et al. Hysteroscopy as a valid tool for endometrial pathology in patients with postmenopausal bleeding or asymptomatic patients with a thickened endometrium: hysteroscopic and histological results. Gynecol. Obstet. Invest. 2015; 79(3): 210-6.
  7. PRACTICE BULLETIN clinical management guidelines for obstetrician-gynecologists. Number 149, April 2015.
  8. Ашрафян Л.А., Киселев В.И. Опухоли репродуктивных органов (этиология и патогенез). М.: Издательство Дмитрейд График Групп; 2007.
  9. Серова Л.Г. Флуоресцентная диагностика у больных с предопухолевой и опухолевой патологией эндометрия: автореф. дисс. канд. мед. наук. М.; 2012.
  10. Чиссов В.И., Филоненко Е.В., ред. Флюоресцентная диагностика и фото динамическая терапия в клинической онкологии. Монография. М.: Триумф; 2012.
  11. Новикова О.В., Новикова Е.Г., Лозовая Ю.А., Чулкова О.В., Пронин С.М. Самостоятельная гормонотерапия как альтернатива хирургическому лечению предрака и начального рака эндометрия у пациенток репродуктивного возраста. Онкогинекология. 2015; 3: 25-33.

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML

Este site utiliza cookies

Ao continuar usando nosso site, você concorda com o procedimento de cookies que mantêm o site funcionando normalmente.

Informação sobre cookies