Uterine microbiota and implantation failure: is there a link?
- 作者: Keburiya L.K.1, Smol’nikova V.Y.1, Priputnevich T.V.1, Murav’eva V.V.1, Trofimov D.Y.1, Shubina E.S.1, Kochetkova T.O.1
-
隶属关系:
- V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
- 期: 编号 7 (2021)
- 页面: 133-143
- 栏目: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/249413
- DOI: https://doi.org/10.18565/aig.2021.7.133-143
- ID: 249413
如何引用文章
详细
全文:
作者简介
Lela Keburiya
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: tati-keburiya@yandex.ru
Ph.D. Student at the Department of Assisted Technologies for the Treatment of Infertility
Veronika Smol’nikova
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: v_smolnikova@oparina4.ru
Dr. Med. Sci., Leading Researcher at the Department of Assisted Technologies for the Treatment of Infertility
Tatiana Priputnevich
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: t_priputnevich@oparina4.ru
Dr. Med. Sci., Director of the Institute of Microbiology, Antimicrobial therapy and Epidemiology
Vera Murav’eva
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: v_muravieva@oparina4.ru
Ph.D. (bio), Researcher at the Institute of Microbiology, Antimicrobial therapy and Epidemiology
Dmitry Trofimov
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: d_troflmov@oparina4.ru
Dr. Bio. Sci., Director of the Institute of Reproductive Genetics
Ekaterina Shubina
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: j_shubina@oparina4.ru
Ph.D. (bio), Head of the Laboratory of Genomic Analysis
Taisya Kochetkova
V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: t_kochetkova@oparina4.ru
Biologist at the Laboratory of Molecular Genetics
参考
- Регистр ВРТ. Отчет за 2017 год.
- Савельева Г.М., Сухих Г.Т., Серов В.Н., Радзинский В.Е., Манухин И.Б., ред. Гинекология. Национальное руководство. 2-е изд. М.: ГЭОТАР-Медиа; 2019.
- Унанян А.Л., Сидорова И.С., Коган Е.А., Белогубова С.Ю., Демура Т.А., Елисаветская А.М., Сизова Н.М. Эндометриоз, аденомиоз, хрониче ский эндометрит: клинико-патогенетические взаимоотношения и репродуктивные неудачи. Акушерство и гинекология. 2018; 10: 136-40.
- Тихончук Е.Ю., Асатурова А.В., Адамян Л.В. Молекулярно-биологические изменения эндометрия у женщин с наружно-генитальным эндометриозом. Акушерство и гинекология. 2016; 11: 42-8. https://dx.doi.org/10.18565/aig.2016.11.42-48.
- Сафронова Н.А., Калинина Е.А., Донников А.Е., Бурменская О.В., Макарова Н.П., Горшинова В.К. Уровень экспрессии гена кальмодули-на в кумулюсных клетках как маркер наличия хромосомных аномалий в эмбрионах в программах экстракорпорального оплодотворения. Акушерство и гинекология. 2016; 10: 64-72. https://dx.doi.org/10.18565/aig.2016.10.64-72.
- Кулакова Е.В., Калинина Е.А., Трофимов Д.Ю., Макарова Н.П., Хечумян Л. Р., Дударова А.Х. Вспомогательные репродуктивные техно -логии у супружеских пар с высоким риском генетических нарушений. Преимплантационный генетический скрининг. Акушерство и гинекология. 2017; 8: 21-7. https://dx.doi.org/10.18565/aig.2017.8.21-27.
- Шафеи Р.А., Сыркашева А.Г.,Романов А.Ю., Макарова Н.П., Долгушина Н.В., Семенова М.Л. Хетчинг бластоцисты у человека. Онтогенез. 2017; 48(1): 8-20.
- Ибрагимова Э.О., Долгушина Н.В., Сыркашева А.Г., Романов А.Ю., Языкова О.И., Макарова Н.П. Роль вспомогательного хетчинга в программах лечения бесплодия методами вспомогательных репродуктивных технологий: обзор литературы. Гинекология. 2016; 18(2): 44-7.
- Perez-Munoz M.E., Arrieta M.C., Ramer-Tait A.E., Walter J. A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: implications for research on the pioneer infant microbiome. Microbiome. 2017; 5(1): 48. https://dx.doi.org/10.1186/s40168-017-0268-4.
- D’Ippolito S., Di Nicuolo F., Pontecorvi A., Gratta M., Scambia G., Di Simone N. Endometrial microbes and microbiome: Recent insights on the inflammatory and immune “players” of the human endometrium. Am. J. Reprod. Immunol. 2018; 80(6): e13065. https://dx.doi.org/10.1111/aji.13065.
- Benner M., Ferwerda G., Joosten I., van der Molen R.G. How uterine microbiota might be responsible for a receptive, fertile endometrium. Hum. Reprod. Update. 2018; 24(4): 393-415. https://dx.doi.ois/10.1093/humupd/dmy012.
- Walther-Antonio M.R., Chen J., Multinu F., Hokenstad A., Distad T.J., Cheek E.H. et al. Potential contribution of the uterine microbiome in the development of endometrial cancer. Genome Med. 2016; 8(1): 122. https://dx.doi.org/10.1186/s13073-016-0368-y.
- Miles S.M., Hardy B.L., Merrell D.S. Investigation of the microbiota of the reproductive tract in women undergoing a total hysterectomy and bilateral salpingooopherectomy. Fertil. Steril. 2017; 107(3): 813-20. e81. https://dx.doi.org/10.1016/j.fertnstert.2016.11.028.
- Chen C., Song X., Wei W., Zhong H., Dai J., Lan Z. et al. The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases. Nat. Commun. 2017; 8(1): 875. https://dx.doi.org/10.1038/s41467-017-00901-0.
- Fang R.L., Chen L.X., Shu W.S., Yao S.Z., Wang S.W., Chen Y.Q. Barcoded sequencing reveals diverse intrauterine microbiomes in patients suffering with endometrial polyps. Am. J. Transl. Res. 2016; 8(3):1581-92.
- Moreno I., Franasiak J.M. Endometrial microbiota - new player in town. Fertil. Steril. 2017; 108(1): 32-9. https://dx.doi.org/10.1016/j.fertnstert.2017.05.034.
- Franasiak J.M., Scott R.T. Endometrial microbiome. Curr. Opin. Obstet. Gynecol. 2017; 29(3): 146-52. https://dx.doi.org/10.1097/GC0.0000000000000357.
- Mitchell C.M., Haick A., Nkwopara E., Garcia R., Rendi M., Agnew K., Fredricks D.N., Eschenbach D. Colonization of the upper genital tract by vaginal bacterial species in nonpregnant women. Am. J. Obstet. Gynecol. 2015; 212(5): 611. e1-9. https://dx.doi.org/10.1016/j.ajog.2014.11.043.
- Moreno I., Codoner F.M., Vilella F., Valbuena D., Martinez-Blanch J.F., Jimenez-Almazan J. et al. Evidence that the endometrial microbiota has an effect on implantation success or failure. Am. J. Obstet. Gynecol. 2016; 215(6): 684-703. https://dx.doi.org/10.1016/j.ajog.2016.09.075.
- Tao X., Franasiak J.M., Zhan Y., Scott R.T., Rajchel J., Bedard J. et al. Characterizing the endometrial microbiome by analyzing the ultra-low bacteria from embryo transfer catheter tips in IVF cycles: next generation sequencing (NGS) analysis of the 16S ribosomal gene. Hum. Microb. J. 2017; 3(12): 15-21. https://dx.doi.org/10.1016/j.humic.2017.01.004.
- Franasiak J.M., Werner M.D., Juneau C.R., Tao X., Landis J., Zhan Y. et al. Endometrial microbiome at the time of embryo transfer: next-generation sequencing of the 16S ribosomal subunit. J. Assist. Reprod. Genet. 2016; 33(1): 129-36. https://dx.doi.org/10.1007/s10815-015-0614-z.
- Zygmunt M., Muzzio D.O. Microorganisms in the healthy upper reproductive tract: from denial to beneficial assignments for reproductive biology. Reprod. Biol. 2019; 19(2): 113-8. https://dx.doi.org/10.1016/j.repbio.2019.04.001.
- Verstraelen H., Vilchez-Vargas R., Desimpel F., Jauregui R., Vankeirsbilck N., Weyers S. et al. Characterisation of the human uterine microbiome in nonpregnant women through deep sequencing of the V1-2 region of the 16S rRNA gene. Peer J. 2016; 4: e1602. https://dx.doi.org/10.7717/peerj.1602.
- Kyono K., Hashimoto T., Kikuchi S., Nagai Y., Sakuraba Y. A pilot study and case reports on endometrial microbiota and pregnancy outcome: An analysis using 16S rRNA gene sequencing among IVF patients, and trial therapeutic intervention for dysbiotic endometrium. Reprod. Med. Biol. 2018; 18(1): 72-82. https://dx.doi.org/10.1002/rmb2.12250.
- Hashimoto T., Kyono K. Does dysbiotic endometrium affect blastocyst implantation in IVF patients? J. Assist. Reprod. Genet. 2019; 36: 2471-9. https://dx.doi.org/10.1007/s10815-019-01630-7.
- Kitaya K., Nagai Y., Arai W., Sakuraba Y., Ishikawa T. Characterization of microbiota in endometrial fluid and vaginal secretions in infertile women with repeated implantation failure. Mediators Inflamm. 2019 May 21; 2019: 4893437. https://dx.doi.org/10.1155/2019/4893437.
- Wee B.A., Thomas M., Sweeney E.L., Frentiu F.D., Samios M., Ravel J. et al. A retrospective pilot study to determine whether the reproductive tract microbiota differs between women with a history of infertility and fertile women. Aust. N. Z. J. Obstet. Gynaecol. 2018; 58(3): 341-8. https://dx.doi.org/10.1111/ajo.12754.