Extramammary Paget’s disease
- 作者: Grekova Y.N.1, Zilberberg N.V.1, Kuznetsova E.I.2
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隶属关系:
- Ural Research Institute of Dermatovenereology and Immunopathology
- P.D. Borodin Verkhnyaya Pyshma Central Town Hospital
- 期: 编号 6 (2022)
- 页面: 176-179
- 栏目: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/249715
- DOI: https://doi.org/10.18565/aig.2022.6.176-179
- ID: 249715
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详细
Background: Extramammary Paget’s disease (EPD) is a rare tumor that most commonly affects the anogenital region. The foci often bear similarities to chronic dermatoses, which can make timely diagnosis difficult. A skin biopsy with histological and immunohistochemical studies is needed to verify the diagnosis of EPD. Most cases are treated with surgical resection, but the recurrence rate remains quite high. Case report: The paper describes a case of an EPD patient whose diagnosis was established 9 years after the onset of the disease. Conclusion: Rare localization, prolonged course, resistance to previous therapy, and pronounced subjective sensations (itching and pain) necessitate a morphopathological study.
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作者简介
Yulia Grekova
Ural Research Institute of Dermatovenereology and Immunopathology
Email: kjn@mail.ru
Dr. Med. Sci., Leading Researcher at the Department of Syphilidology and Sexually Transmitted Infections
Natalya Zilberberg
Ural Research Institute of Dermatovenereology and Immunopathology
Email: zilberberg@mail.ru
Dr. Med. Sci., Professor, Deputy Director for Research
Ekaterina Kuznetsova
P.D. Borodin Verkhnyaya Pyshma Central Town Hospitalgeneral practitioner
参考
- Crocker H.R. Paget’s disease affecting the scrotum and penis. Trans. Pathol. Soc. Lond. 1889; 40: 187-91.
- Lam C., Funaro D. Extramammary Paget’s disease: Summary of current knowledge. Dermatol. Clin. 2010; 28(4): 807-26. https://dx.doi.org/10.1016/j.det.2010.08.002.
- Parker L.P., Parker J.R., Bodurka-Bevers D., Deavers M., Bevers M.W., Shen-Gunther J., Gershenson D.M. Paget’s disease of the vulva: pathology, pattern of involvement, and prognosis. Gynecol. Oncol. 2000; 77(1): 183-9. https://dx.doi.org/10.1006/gyno.2000.5741.
- Mengjun B., Zheng-Qiang W., Tasleem M.M. Extramammary Paget’s disease of the perianal region: a review of the literature emphasizing management. Dermatol. Surg. 2013; 39(Pt. 1): 69-75. https://dx.doi.org/10.1111/dsu.12019.
- Trofymenko O., Garcia V., Zeitouni N.C. Primary extramammary Paget’s disease of the skin: treatment and survival. Int. J. Dermatol. 2018; 57(1): e76-8. https://dx.doi.org/10.1111/ijd.14105.
- Wagner G., Sachse M.M. Extramammary Paget disease - clinical appearance, pathogenesis, management. J. Dtsch. Dermatol. Ges. 2011; 9(6): 448-54. 10.1111/j.1610-0387.2010.07581.x.
- Blasco-Morente G.,Martin-Castro A., Garrido-Colmenero C., Tercedor-Sancheza J. Extramammary Paget disease: A report of 10 cases. Actas Dermosifiliogr. 2015; 106(1): e1-5.
- Ishizuki, S., Nakamura Y. Extramammary Paget’s disease: diagnosis, pathogenesis, and treatment with focus on recent developments. Curr. Oncol. 2021; 28(4): 2969-86. https://dx.doi.org/10.3390/curroncol28040260.
- Scarbrough C.A., Vrable A., Carr D.R. Definition, association with malignancy, biologic behavior, and treatment of ectopic extramammary Paget’s disease: A review of the literature. J. Clin. Aesthet. Dermatol. 2019; 12(8): 40-4.
- St Claire K., Hoover A., Ashack K., Khachemoune A. Extramammary Paget disease. Dermatol. Online J. 2019; 25(4): 13030/qt7qg8g292.
- Simonds R.M., Segal R.J., Sharma A. Extramammary Paget’s disease: A review of the literature. Int. J. Dermatol. 2019; 58(8): 871-9. https://dx.doi.org/10.1111/ijd.14328.
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