Vol XLIV, No 3 (2012)

In the article it is analyzed the mistake of the psychopathological conception of ethiopatogenesis of craving, being basic in the Russian Federation. Treatment standards, based on this false conception, were criticized. The data of scientific research are given, including the Cochreian reviews specifying the necessity of use of preparations with confirmed efficiency and safety in opioid addiction therapy.

Based on the literature and our own experimental data, various neuropsychological aspects of aggression and suicidal behavior are discussed. In individuals with suicidal behavior significant changes of the functional brain asymmetry in all levels - metabolic, structural and functional - are observed. Lateralization profile changes in suicidal behavior include motor, sensory and cognitive asymmetry. Persons with suicidal behavior are likely to have their own neuropsychological patterns that differ from those without suicidal behavior. The dependence between level of aggressiveness and hostility and the preponderance of the left motor and sensory profiles of asymmetry together with the predominance of right-hemisphere activity have been found. These data indicate to the existence of a correlation between brain asymmetry and human aggression.

In this article we present the results of treatment of 84 outpatients with schizophrenic disorders, who systematically take alcohol. All patients were divided into three groups. The treatment in different groups of patients included: emotional stress therapy, psychopharmacological treatment and psychosocial intervention improvement (long-termpsychotherapy, occupation therapy, social rehabilitation measure). After one year of treatment, the effectiveness of treatment was assessed. The significant differences among all three groups were found in quantity and quality of substance abuse remission, severity of leading psychiatric symptoms, hospital therapy frequency and indicators of social functioning.

The paper describes the results of the research of 282 patients with panic disorder who were studied by clinical and psychopathological method. The various options of comorbidity of panic disorder with other mental and behavioral disorders were found in 249 of them. Clinical manifestations of panic disorder in cases of comorbidity with social phobia, posttraumatic stress, conversion, depressive, schizotypal disorder and alcohol dependence are described in the article.

In order to determine the effect of antihistamines of II generation on the cognitive function of patients with chronic urticaria, 88 patients of mild and moderate severity of CU were examined. Patients took a basic therapy of histamine receptor blockers of II generation. The effectiveness of therapy was assessed by the dynamics of the main clinical symptoms and cognitive changes with the test to assess attention (Krepelin-Shulte) and a test to assess the activity of thinking by I.M. Luschihina. We observed decrease of cognitive function in patients, who took cetirisin and levocetirisine.

Presented was the generalized data on the forecast of the epilepsy. They include: form of epilepsy, character of attacks, age of the disease debut, and presence of cerebral structural changes. It was shown the significance of modern and adequate treatment, performed by anti-epileptic drugs

The review of the modern literature on main neuropsychiatric disorders was given: delirium, mania, "catastrophic reaction", pseudobulbar affect, depression, behavioral disorders and dementia. Questions of prevalence, clinical displays and diagnostics of clinical phenomena are discussed. Opinions on localization of mental symptoms in a brain are discussed at stroke, and on associations with other infringements.

In the article modern representations, classification and diagnostic criteria of cerebellar ataxia of late age with the sporadic onset are stated; features of clinic, diagnostics and treatment of symptomatic (acquired or secondary) neurodegenerative processes of a cerebellum are considered; the characteristic of pathogenetic and morphological aspects of development local cortical cerebellar atrophy at persons of late age is given. For the characteristic of secondary acquired cerebellar degeneration the term «symptomatic cerebellopathy» is offered, allowing to distinguish local cortical atrophy of cerebellum and immediate spinocerebellar degenerative diseases hereditary and idiopathic origin.

The survey of home and foreign literature is given in the article. It is devoted to the problems of clinical and social preconditions of criminal behavior of patients with organic mental disorders. More precise and early determination of the factors, influencing delinquency of such patients would make more clear prerequisites of their socialization, to develop medico-rehabilitation programs as preventative measures of delinquent behavior. The most notional predictors of negative crime prognosis are social functioning factors.