Microcapsules in medicine: review of scientific literature and prospects of application in microencapsulation of anticancer drugs

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Abstract

Microcapsules are an innovative form of drug delivery into the human body, which has attracted attention due to its great capabilities in various fields of healthcare. These small particles with a special shell have the potential to improve the processes of drug therapy, diagnosis, and treatment of diseases (for example, cancer), during which the effectiveness increases and the toxicity of many drugs decreases. Due to their small size (from 100 to 500 microns), microcapsules can transfer and protect the active components of drugs, ensuring their accurate and targeted delivery to the site of action in the body. Currently, a promising area is the study of microcapsules in which antitumor drugs are placed. The active substance is delivered directly to cancer cells, which increases the concentration of the drug in the tumor and at the same time reduces its effect on healthy tissues. This approach will help improve cancer treatment outcomes and increase the chances of a successful recovery for patients without any dangerous side effects.

The purpose of the work is to analyze modern research related to the microcapsulation of various drugs, especially in the field of oncology.

The literature is analyzed, including scientific domestic and foreign publications that have been written over the past ten years. The analysis of existing studies related to the use of microcapsules in medicine is presented. Some methods of obtaining a new form, its types, and applications in medicine, in particular in oncology, are considered. This review provides valuable information on a variety of research methods and promising uses of a process such as microcapsulation for the delivery of anticancer drugs, and can be one of the important resources for researchers developing new therapeutic approaches, as well as for doctors applying advanced cancer treatments through innovative therapies.

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About the authors

A. K. Sapronova

Kursk State Medical University

Author for correspondence.
Email: nastcapronova@mail.ru

Post-graduate Student, Department of Pharmacology

Russian Federation, Kursk

T. A. Denisyuk

Kursk State Medical University

Email: denitatyana@yandex.ru

Dr.Sc. (Med.), Professor of the Department of Pharmacology

Russian Federation, Kursk

O. S. Lositskaya

Tambov State University named after G.R. Derzhavin

Email: lesenok2811@mail.ru

Ph.D. (Biol.), Associate Professor of the Department of Pharmacology and Biochemistry

Russian Federation, Tambov

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