The level of expression of progesterone, estradiol and Vitamin D receptors in mononuclear cells of the peripheral blood of patients with surgical menopause
- Authors: Kruchinina E.V1, Gorenkova O.S1, Kochina N.A2, Krasnoshchok E.V2, Glazkova A.V1, Polyakova E.Y.3, Zaydieva Y.Z1, Kareva E.N2,4, Serebrova S.Y.2,5
-
Affiliations:
- Moscow Regional Research Institute of Obstetrics and Gynecology
- N.I. Pirogov Russian National Research Medical University
- M.F. Vladimirsky Moscow Regional Research Clinical Institute
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- Scientific Centre for Expert Evaluation of Medicinal Products
- Issue: Vol 18, No 1 (2020)
- Pages: 61-64
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2918/article/view/113214
- DOI: https://doi.org/10.29296/24999490-2020-01-10
- ID: 113214
Cite item
Abstract
Full Text
![Restricted Access](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_lock.png)
About the authors
E. V Kruchinina
Moscow Regional Research Institute of Obstetrics and Gynecology
O. S Gorenkova
Moscow Regional Research Institute of Obstetrics and Gynecology
N. A Kochina
N.I. Pirogov Russian National Research Medical University
E. V Krasnoshchok
N.I. Pirogov Russian National Research Medical University
A. V Glazkova
Moscow Regional Research Institute of Obstetrics and Gynecology
E. Yu Polyakova
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Y. Z Zaydieva
Moscow Regional Research Institute of Obstetrics and Gynecology
E. N Kareva
N.I. Pirogov Russian National Research Medical University; I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: elenakareva@mail.ru
S. Yu Serebrova
N.I. Pirogov Russian National Research Medical University; Scientific Centre for Expert Evaluation of Medicinal Products
References
- Shalhoub V, Elliott G., Chiu L., Manoukian R., Kelley M., Hawkins N., Davy E., Shimamoto G., Beck J., Kaufman S.A., Van G., Scully S., Qi M., Grisanti M., Dunstan C., Boyle WJ., Lacey D.L. Characterization of osteoclast precursors in human blood," British Journal of Haematology 2000; 111 (2): 501-12.
- Takayanagi H. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nature Reviews Immunology 2007; 7 (4): 292-304.
- Nicholson G.C., Malakellis M., Collier FM., Cameron PU., Holloway WR., Gough TJ., Gregorio-King C., Kirkland M.A., Myers D.E. Induction of osteoclasts from CD14-positive human peripheral blood mononuclear cells by receptor activator of nuclear factor kB ligand (RANKL). Clinical Science. 2000; 99 (2): 133-40.
- Mosheimer B.A., Kaneider N.C., Feistritzer C., Sturn D.H., and Wiedermann C.J. Expression and function of RANK in human monocyte chemotaxis. Arthritis & Rheumatism. 2004; 50 (7): 2309-16.
- Li X., Qin L., Bergenstock M., Bevelock L.M., Novack D.V., and Partridge N.C. Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclasts. The J. of Biological Chemistry. 2007; 282 (45): 33098-106.
- Wright L.M., Maloney W, Yu X., Kindle L., Collin-Osdoby P., and Osdoby P. Stromal cell-derived factor-1 binding to its chemokine receptor CXCR4 on precursor cells promotes the chemotactic recruitment, development and survival of human osteoclasts. Bone. 2005; 36 (5): 840-53.
- Ishii M., Kikuta J., Shimazu Y., Meier-Schellersheim M., and Germain R.N. Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo. The J. of Experimental Medicine. 2010; 207 (13): 2793-8.
- Kikuta J., Ishii M. Osteoclast migration, differentiation and function: Novel therapeutic targets for rheumatic diseases. Rheumatology. 2013; 52 (20): 226-34.
- Daswani B., Khatkhatay M.I. «Omics» Signatures in Peripheral Monocytes from Women with Low BMD Condition. J. of Osteoporosis. 2018, Article ID 8726456, 7 pages. https://doi.org/10.1155/2018/8726456
- Salamanna F., Maglio M., Giavaresi G., Pagani S., Giardino R., and Fini M. In vitro method for the screening and monitoring of estrogen-deficiency osteoporosis by targeting peripheral circulating monocytes. Age (Dordrecht Netherlands). 2015; 37: 9819.
- Boyum A. Separation of leukocytes from blood and bone marrow. Scand. J. Lab. Investig. 1968; 21 (97): 1-9.
- Livak K.J., Schmittgen T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-55C(T)) method. Methods. 2001; 25: 402-8.
- Hughes G.C. Progesterone and Autoimmune Disease. Autoimmun Rev. 2012; 11 (6-7): 502-14.
- Карева Е.Н., Ганковская Л.В., Шимановский Н.Л. Половые стероиды и иммунитет. Российский иммунологический журнал. 2012; 1: 3-14.
- Cvoro A., Tatomer D., Tee M.K., Zogovic T, Harris HA, Leitman DC. Selective estrogen receptor-beta agonists repress transcription of proinflammatory genes. Immunol. 2008; 180 (1): 630-6.
- Ray R., Novotny N.M., Crisostomo PR., Lahm T., Abarbanell A., Meldrum D.R. Sex Steroids and Stem Cell Function. Mol. Med. 2008; 14 (7-8): 493-501.
- Gavali S., Gupta M.K., Daswani B., Wani M.R., Sirdeshmukh R., Khatkhatay M.I.Estrogen enhances human osteoblast survival and function via promotion of autophagy. Biochim Biophys Acta Mol Cell Res. 2019; pii: S0167-4889 (19) 30106-5. https:// doi.org/10.1016/j.bbamcr.2019.06.014.
- Kongsbak M., Levring T.B., Geisler C., and von Essen M. R. The Vitamin D Receptor and T Cell. Function. Front Immunol. 2013; 4: 148. Published online 2013 Jun 18. https://doi.org/10.3389/ fimmu.2013.00148
Supplementary files
![](/img/style/loading.gif)