Etiological structure and antibiotic sensitivity of uropathogens in chronic recurrent infection of the lower urinary tract


Cite item

Full Text

Abstract

While acute infections of the lower urinary tract (UT) have been studied in detail and antibiotic therapy of such infections is well known, etiology and choice of antibacterial treatment in recurrent chronic UT infection are not so clear. In our trial we aimed at elucidation of etiological structure of chronic cystitis recurrences by means of microbiological investigation of urine samples from 72 women on extended spectrum of nutrient media. In all the cases urine was infected with both aerobic and non-clostridial anaerobic bacteria. We determined prevalent pathogens and their antibiotic sensitivity and compared them with standard pathogens and their sensitivity in acute lower UT infection. We came to the conclusion that it is necessary to develop new recommendations on antibiotic treatment of recurrent chronic cystitis in women.

References

  1. Piljic D., Ahmetagic S., Zildzic M. et al. Etiological factors of community acquired urinary tract infection in hospitalized patients. Med. Arh. 2009; 63 (3): 128-132.
  2. Gorbach S. L., Barlett J. G., Blacklow N. R. Infectious diseases. 1992.
  3. Wein A. J., Kavoussi L. R., Novick A. C. et al. Campbell-walsh urology. Philadelphia; 2010.
  4. Murray P. R., Rosenthal K. S., Pfaller M. A. Medical microbiology. Philadelphia; 2005.
  5. Czaja C. A., Stamm W. E., Stapleton A. E. et al. Prospective cohort study of microbial and inflammatory events immediately preceding Escherichia coli recurrent urinary tract infection in women. J. Infect. Dis. 2009; 200 (4): 528-536.
  6. Пушкарь Д. Ю., Зайцев А. В., Лоран О. Б. и др. Особенности современной антибактериальной терапии при рецидивах цистита у женщин пременопаузального возраста. Фарматека 2006; 10: 3-5.
  7. Cai T., Mazzoli S., Nesi G. et al. 14-day prulifloxacin treatment of acute uncomplicated cystitis in women with recurrent urinary tract infection: a prospective, open-label, pilot trial with 6-month follow-up. J. Chemoter. 2009; 21 (5): 535-541.
  8. European Association of Urology. Gudelines on urological infection. 2010.
  9. Ulett K. B., Benjamin W. H., Zhuo F. et al. Diversity of group B streptococcus serotypes causing urinary tract infection in adults. J. Clin. Microbiol. 2009; 47 (7): 2055-2060.
  10. Меньшиков В. В. Методики клинических лабораторных исследований. М.: Лабора; 2009.
  11. Бухарин О. В. Экология микроорганизмов человека. Екатеринбург; 2006.
  12. Гриценко В. А., Иванов Ю. Б. Роль персистентных свойств микроорганизмов в патогенезе эндогенных инфекций. Журн. микробиол. 2009; 4: 66-71.
  13. Nauseef W. M. How human neutrophilis kill and degrade microbes an integrate view. Immunol. Rev. 2007; 219: 88-102.
  14. Relman D. A. New technologies, human-microbe interactions, and the search for previously unrecognized pathogens. J. Infect. Dis. 2002; 186 (2): 254-258.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies