Radiodiagnosis of early-stage nephroangiopathy in children with arterial hypertension


Cite item

Full Text

Abstract

A total of 115 children aged 13-17 years (mean age 15.77 ± 1.89 years, 98 boys and 17 girls) with essential arterial hypertension (EAH) were examined. Of them, 70 children had stable arterial hypertension (SAH), 45 children - labile arterial hypertension (LAH). 24-h monitoring of blood pressure, triplex ultrasound study of the renal vessels were performed in all the patients. The assessment of renal hemodynamics showed that blood flow was more active in SAH patients. The clinostatic test revealed inhibition of circulation at the level of the basic trunk (by 26% in SAH and by 22% in LAH) and segmentary renal arteries (by 28% in SAG), IR ( < 0.52). The above findings confirm the action of arterioveinous bypass blood flow mechanism and provide diagnosis of nephroangiopathy at early stages of EAH.

References

  1. Medical Research Council Working Party. MRC trial of treatment of mild hypertension: principal results. Br. Med. J. 1985; 291: 97-104.
  2. Medical Research Council Working Party. MRC trial of treatment of hypertension in older adults: principal results. Br. Med. J. 1992; 304: 405-412.
  3. Heart Outcomes Prevention Evaluation (HOPE) Study investigators. Effects of angiotensin converting enzyme inhibitor, ramipril on cardiovascular events in high risk patients. N. Engl. J. Med. 2000; 342: 145-153.
  4. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the systolic hypertension in the elderly program (SHEP). J. A. M. A. 1991; 265: 3255- 3264.
  5. Hansson L., Zanchctti A., Carrulhcrs S. et al. Effects of intensive blood pressure lowering and low dose spirin in patients with hypertension: principal results of the hypertension optimal treatment (HOT) randomized trial. Lancet 1998; 351: 1755-1762.
  6. Буланов М. Н. и др. Показатели внутрипочечной гемодинамики как маркеры доклинической стадии гипертонической нефропатии. Ультразвук. и функц. диагн. 2002; 2: 18-23.
  7. Pontremoli R., Viazzi F. Increased renal resistive index in patients with essential hypertension: a marker of target organ damage. Nephrol. Dial. Transplant. 1999; 14 (2): 360-365.
  8. Смольянинова Н. Г. Оценка почечного кровотока УЗ методами исследования с применением компьютерного анализа при различных формах артериальной гипертонии: Автореф. дис. ... канд. мед. наук. М.; 1998.
  9. Нанчикеева М. Л. Ранняя стадия поражения почек у больных гипертонической болезнью: клиническое значение, принципы профилактики: Автореф. дис. ... д-ра мед. наук. М.; 2010.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2011 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies