ASSESSMENT OF THE RISK OF INCIDENTAL PROSTATE CANCER PROGRESSION
- Authors: Marisov L.V1, Vinarov A.Z1, Alyaev Y.G1, Gerasimov A.N1, Bezrukov E.A1
-
Affiliations:
- SBEI HPE First MSMU n.a. I.M. Sechenov
- Issue: No 5 (2015)
- Pages: 43-45
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/282234
- ID: 282234
Cite item
Open Access
Access granted
Abstract
At present, methodology based on the stage T1a or T1b is used to determine the risk of incidental prostate cancer (IPC) progression. This approach was developed before the introduction of prostate-specific antigen (PSA) into the practice of the urologist, and does not account of the degree of IPC. For the prediction of IPC progression, multifactorial prognostic model was created. This model is based on the analysis of two parameters - the total PSA level before the surgery and the Gleason score according to the results of morphological examination after transurethral resection of the prostate hyperplasia. This model has a high predictive value (AUC 86.6%) and can be easily used in practice. For the interpretation of the calculated results special table is formed that allows to assess the risk of progression over the next 3.5 years.
Full Text
About the authors
L. V Marisov
SBEI HPE First MSMU n.a. I.M. Sechenov
Email: marisov51@mail.ru
urologist at the urology clinic №2 ACH
A. Z Vinarov
SBEI HPE First MSMU n.a. I.M. Sechenov
Yu. G Alyaev
SBEI HPE First MSMU n.a. I.M. Sechenov
A. N Gerasimov
SBEI HPE First MSMU n.a. I.M. Sechenov
E. A Bezrukov
SBEI HPE First MSMU n.a. I.M. Sechenov
References
- Марисов Л.В., Винаров А.З. Диагностика и лечение инцидентального рака простаты. Урология. 2014;3:82-85.
- Лопаткин Н.А. Урология: национальное руководство. М.: ГЭОТАР-Медиа. 2009. 1024 с.
- Tombal B., De Visccher L., Cosyns J.P., Lorge F., Opsomer R., Wese F.X., Van Cangh P.J. Assessing the risk of unsuspected prostate cancer in patients with benign prostatic hypertrophy: a 13-year retrospective study of the incidence and natural history of T1a-T1b prostate cancers. BJU Int. 1999;84(9):1015-1020.
- Allué López M., Allepuz Losa C., Borque Fernando A., Serrano Frago P., Gil Martinez P., Gil Sanz M.J., Rioja Sanz L.A. [Incidental prostatic cancer: T1a-T1b. Our experience after observation/radical surgery and literature review]. Actas Urol Esp. 2006;30(8):749-753.
- Capitanio U., Scattoni V., Freschi M., Briganti A., Salonia A., Gallina A., Colombo R., Karakiewicz P.I., Rigatti P., Montorsi F. Radical prostatectomy for incidental (stage T1a-T1b) prostate cancer: analysis of predictors for residual disease and biochemical recurrence. Eur Urol. 2008;54(1):118-125.
Supplementary files
