Impact of germline BRCA2 and CHEK2 mutations on time to castration resistance in patients with metastatic hormone-naive prostate cancer
- Authors: Matveev V.B1, Kirichek A.A1, Filippova M.G1, Savinkova A.V1, Khalmurzaev O.A1, Lyubchenko L.N1
-
Affiliations:
- N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
- Issue: No 5 (2019)
- Pages: 79-85
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/312295
- DOI: https://doi.org/10.18565/urology.2019.5.79-85
- ID: 312295
Cite item
Abstract
Full Text
About the authors
V. B Matveev
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
A. A Kirichek
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: akirdoctor@gmail.com
M. G Filippova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
A. V Savinkova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
O. A Khalmurzaev
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
L. N Lyubchenko
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
References
- Bray F., Ferlay J., Soerjomataram I., et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018:68(6):394-424. doi: 10.3322/caac.21492.
- Cornford P., Bellmunt J., Bolla M. et al. EAU-ESTRO-SIOG guidelines on prostate cancer. Part II: Treatment of relapsing, metastatic, and castration-resistant prostate cancer. Eur Urol. 2017;71(4):630-642. Doi: 10.1016/j. euuro.2016.08.002.
- Harris W.P., Mostaghel E.A., Nelson P.S., et al. Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion. Nat Clin Pract Urol. 2009;6(2):76-85. Doi: 10.1038/ ncpuro1296.
- Wu J.N., Fish K.M., Evans C.P. et al. No improvements noted in overall or causespecific survival in patients presented with metastatic prostate cancer over a 20-year period. Cancer 2014;120(6):818-23. Doi: 10.1002/ cncr.28485.
- Siegel R.L., Miller K.D., Jemal A. Cancer Statistics, 2017. CA Cancer J Clin. 2017;67(1):7-30.
- Glass T.R., Tangen C.M., Crawford E.D., Thompson I. Metastatic carcinoma of the prostate: identifying prognostic groups using recursive partitioning. J Urol. 2003;169(1):164-169. doi: 10.1097/01.ju.0000042482.18153.30.
- Киричек А.А., Камолов Б.Ш., Матвеев В.Б. Обзор материалов конгресса Европейского общества медицинской онкологии (ESMO) 2017 г. Онкоурология. 2017;13(4): 133-140. https://doi.org/10.17650/1726-9776-2017-13-4-133-140
- Vale C.L., Burdett S., Rydzewska L.H., et al. Addition of docetaxel or bisphosphonates to standard of care in men with localised or metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggregate data. Lancet Oncol. 2016;17(2):243-56. doi: 10.1016/S1470-2045(15)00489-1.
- Rydzewska, L.H.M., Burdett S., Vale C.L., et al. Adding abiraterone to androgen deprivation therapy in men with metastatic hormone-sensitive prostate cancer: A systematic review and meta-analysis. Eur J Cancer. 2017;84:88-101. doi: 10.1016/j.ejca.2017.07.003.
- Алексеев Б.Я., Андрианов А.Н., Каприн А.Д. Современные подходы к выбору терапии 1-й линии больных метастатическим гормоночувствительным раком предстательной железы. Онкоурология. 2017;13(4):85-90. https://doi.org/10.17650/1726-9776-2017-13-4-85-90
- Sweeney C., Chen Y., Liu G., et al. Long term efficacy and QOL data of chemohormonal therapy (C-HT) in low and high volume hormone naive metastatic prostate cancer (PrCa). Ann Oncol 2016;27(6):243-265.
- De Bono J.S., Ashworth A. Translating cancer research into targeted therapeutics. Nature. 2010;467(7315):543-9. doi: 10.1038/nature09339.
- Castro E., Goh C., Olmos D., et al. Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. J Clin Oncol. 2013;31(14):1748-1757.
- Alanee S.R., Glogowski E.A., Schrader K.A., et al. Clinical features and management of BRCA1 and BRCA2-associated prostate cancer. Front Biosci (Elite Ed). 2014;6:15-30.
- Castro E., Goh C., Leongamornlert D., et al. Effect of BRCA mutations on metastatic relapse and cause-specific survival after radical treatment for localized prostate cancer. Eur Urol. 2015;68(2):186-193.
- Матвеев В.Б., Киричек А.А., Савинкова А.В. и др. Влияние герминальных мутаций в гене CHEK2 на выживаемость до биохимического рецидива и безметастатическую выживаемость после радикального лечения у больных раком предстательной железы. Онкоурология. 2018;14(4):53-67. https://doi.org/10.17650/1726-9776-2018-14-4-53-67
- Киричек А.А., Камолов Б.Ш., Саве'лов Н.А., Матвеев В.Б. О стадировании онкоурологических заболеваний по обновленной TNM-классификации 8-го издания. Онкоурология. 2018;14(1):166-172. https://doi.org/10.17650/1726-9776-2018-14-1-166-172
- Mateo J., Boysen G., Barbieri C.E., et al. DNA repair in prostate cancer: biology and clinical implications. Eur Urol. 2017;71 (3):417-425. doi: 10.1016/j.eururo.2016.08.037
- Pritchard C.C., Mateo J., Walsh M.F., et al. Inherited DNA-repair gene mutations in men with metastatic prostate cancer. N Engl J Med. 2016;375(5):443-53. doi: 10.1056/NEJMoa1603144.
- Annala M., Struss W.J., Warner E.W., et al. Treatment outcomes and tumor loss of heterozygocity in germline DNA repair-deficient prostate cancer. Eur Urol. 2017;72(1):34-42. doi: 10.1016/j.eururo.2017.02.023.
- Antonarakis E.S., Lu C., Luber B., et al. Germline DNA-repair gene mutations and outcome in men with metastatic castration-resistant prostate cancer receiving first-line abiraterone and enzalutamide. Eur Urol. 2018;74(2):218-225. doi: 10.1016/j.eururo.2018.01.035.
- Antonarakis E.S., Shaukat F., Isaacsson Velho P., et al. Clinical features and therapeutic outcomes in men with advanced prostate cancer and DNA mismatch repair gene mutations. Eur Urol. 2018; S0302-2838(18)30750-4. doi: 10.1016/j.eururo.2018.10.009. PMID: 30337059.
- Castro E.M., Romero Laorden N., Piulats Rodriguez J.M., et al. LBA32 PROREPAIR-B: a prospective cohort study of DNA repair defects in metastatic castration resistant prostate cancer (mCRPC). Ann Oncol 2017:28, http://dx.doi.org/10.1093/annonc/ mdx440.025.
- Ma Y., He L., Hyang Q., et al. Response to olaparib in metastatic castration-resistant prostate cancer with germline BRCA2 mutation: a case report. BMC Med Genet. 2018:19(1):185. doi: 10.1186/s12881-018-0703-9.
- Gongora A.B.L., Canedo F.S.N.A., de Melo A.L.A., et al. Tumor lysis syndrome after platinum-based chemotherapy in castration-resistance prostate cancer with a BRCA2 mutation: a case report. Clin Genitourin Cancer. 2019;17(1):e61-e64. doi: 10.1016/j.clgc.2018.09.001.
- Purshouse K., Schuh A., Fairfax B.P., et al. Whole-genome sequencing identifies homozygous BRCA2 deletion guiding treatment in dedifferentiated prostate cancer. Cold Spring Harb Mol Case Stud. 2017;3(3):a001362. doi: 10.1101/mcs.a001362.
- Ramos J.D., Mostaghel E.A., Pritchard C.C., Yu E.Y. DNA repair pathway in metastatic castration-resistant prostate cancer responders to radium-223. Clin Genitourin Cancer. 2018;16(2):106-110. Doi: 10.1016/j. clgc.2017.11.009.