Correlation adaptometry as a method of renal assessment and organismic interaction with closed kidney injury

Introduction. The kidney concussion causes damage to intraorganic angioarchitectonics, microcirculatory disorders, as a consequence - a decrease in functional capabilities of the organ, affecting inter-system interrelationships in the organism. Purpose of the study: to evaluate the interaction of renal functions and hemodynamic homeostasis by the method of correlation adaptometry in groups of victims after closed kidney injury with different areas of organ damage. Materials and methods. The study involved 114 patients with isolated comotional kidney injury Grade I-III, with the involvement of the 1st organ segment - 30 (26.0%), 2 segments - 26 (22.8%), 3 segments - 58 (51.2%). A radionuclide study was performed, the parameters of hemodynamic homeostasis were determined, and the functional stress index (IFN) was calculated. The assessment of the contingency of the analyzed parameters was carried out on the basis of correlation analysis, and the degree of connectivity of the parameters was estimated using the correlation graph. Results. It was found that with an increase in the number of damaged segments of the kidney, the main physiological parameters of the organ regress together with an increase in functional deficit. Vector decrease of functional capabilities ofthe organism by IFN was noted: from satisfactory adaptation (when kidney segment 1 was injured); through tension of adaptation mechanisms (2 segments); to unsatisfactory adaptation (3 segments), when homeostasis was preserved with significant tension of regulatory systems. The correlation graph was recorded at the level of 11,96 and 11,57 in trauma of the 1st and 2nd segments of the kidney. In case of damage to 3 segments of the organ, the weight of the correlation graph increases - 16,97, which indicates pronounced structural and functional maladaptive disorders in the activity of the organ. Conclusion: assessment of the conjugacy of indicators of renal and organism interaction, indicates the greatest tension of the reserves of functional potential of the organism in case of damage of 3 segments of the kidney.

closed kidney injury, kidney segments, homeostasis, functional stress index, correlation adaptometry