THE ROLE OF THE RANDALL’S PLAQUES IN THE PATHOGENESIS OF RECURRENT UROLITASIS


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Abstract

The aim of the work was to present current concept of the pathogenesis of urolithiasis. Treatment and prevention of this disease a challenging issue. The article presents basic information about Randall’s plaques that are described as calcium salt deposits on the surface of the transitional cell epithelium. The cause of Randall’s plaques was the subject of many studies and is still not completely clear. To date, we can state that the deposit formation starts in the pelvicalyceal system and is directly linked to recurrent urolithiasis. The discovery of Randall plaques in the 1940s transformed the conception of stone formation, but there are even more questions about the pathogenesis of urolithiasis. In that respect, we consider it important to analyze the studies on Randall’s plaques.

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About the authors

A. A Kamalov

Lomonosov MSU

Email: armais.kamalov@rambler.ru
Academician of the RAS, Dr.Med.Sci., Prof., Director of the Medical Research and Educational Center, Head of the Department of Urology and Andrology, Faculty of Fundamental Medicine Moscow, Russia

D. A Okhobotov

Lomonosov MSU

Email: 14032007m@gmail.com
Ph.D., Urologist and Senior Researcher at the Research Department of Urology and Andrology of the of the Medical Research and Educational Center, Scientific Secretary of the Russian Society «Men’s Health» Moscow, Russia

A. N Nizov

Lomonosov MSU

Email: nizovale@gmaiI.com
Urologist at the Medical Research and Educational Center, Ph.D. Student at the Faculty of Fundamental Medicine Moscow, Russia

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