Features of nephrotransplant blood flow during kidney transplant
- Authors: Dunaevskaya S.S.1,2, Kosik A.A.1,2, Kuchkarov M.F.2, Repina E.V.2, Popov I.S.1
-
Affiliations:
- Krasnoyarsk State Medical University
- Federal Siberian Scientific and Clinical Center FMBA of Russia
- Issue: No 2 (2023)
- Pages: 53-57
- Section: Original Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/521899
- DOI: https://doi.org/10.18565/urology.2023.2.53-57
- ID: 521899
Cite item
Abstract
Introduction. Kidney transplantation, which provides a high quality of life for patients with terminal chronic renal failure worldwide, is recognized as one of the main achievements of modern medicine. Graft dysfunction is an urgent problem, the one-year survival rate of renal transplants is from 93% (from cadaveric donors) to 97% (from living donors), the five-year survival rate is on average 95%.
The aim of the study consisted in determining the features of renal graft blood flow in the early post-transplantation period.
Materials and methods. The results of operative treatment of 110 patients who underwent orthotopic kidney transplantation for various reasons were analyzed. The indication for transplantation was chronic kidney disease of 5 st in the outcome of the main disease: in 70 (64%) in chronic glomerulonephritis, in 22 (20%) patients in autosomal dominant polycystic kidney disease, 10 (9%) patients in diabetic nephropathy, in 8 (7%) patients in chronic pyelonephritis. The five-year survival rate of the renal graft during catamnestic follow-up was 88%. All patients underwent ultrasound dopplerography of a renal graft in dynamics from the first day to discharge.
Results. After transplantation of a renal graft, blood flow disorders are caused by swelling in the early postoperative period, but further to discharge there was a normalization of the blood flow rates of the renal graft. Which suggests a satisfactory functional state of the renal graft and is a favorable prognostic feature. Reduced blood flow in the graft and increased resistance index (RI) in ultrasound with dopplerography are signs of developing graft dysfunction.
Conclusion. In almost all cases, postoperative postoperative renal transplant transplants continued to cause blood flow disturbances due to early postoperative edema. The use of ultrasound and Doppler imaging to assess graft status is a diagnostically valuable non-invasive method.
Full Text
![Restricted Access](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_lock.png)
About the authors
S. S. Dunaevskaya
Krasnoyarsk State Medical University; Federal Siberian Scientific and Clinical Center FMBA of Russia
Author for correspondence.
Email: vikto-potapenk@yandex.ru
Ph.D., MD, professor, professor at the Department of General Surgery named after M.I. Gul’man
Russian Federation, Krasnoyarsk; KrasnoyarskA. A. Kosik
Krasnoyarsk State Medical University; Federal Siberian Scientific and Clinical Center FMBA of Russia
Email: arina.kosik@mail.ru
Ph.D. student at Department of General Surgery named after M.I. Gul’man
Russian Federation, Krasnoyarsk; KrasnoyarskM. F. Kuchkarov
Federal Siberian Scientific and Clinical Center FMBA of Russia
Email: mfk45@mail.ru
Head of the Department of Surgery
Russian Federation, KrasnoyarskE. V. Repina
Federal Siberian Scientific and Clinical Center FMBA of Russia
Email: elerepina@yandex.ru
physician of ultrasound diagnostics
Russian Federation, KrasnoyarskI. S. Popov
Krasnoyarsk State Medical University
Email: igor-popov-2000@mail.ru
student
Russian Federation, KrasnoyarskReferences
- Abaeva O.P., Romanov S.V., Ryabova E.N. Quality of life of patients undergoing kidney and liver transplant surgery. Preventive medicine. 2020;1(23):121–126.
- Vatazin A.V., Zul’karnaev A.B., Krstich M. 2012. Septic bacterial complications after kidney transplantation. Academic Journal of Western Siberia. 2012;1:17–17a.
- Berezhnoy A.G., Dunaevskaya S.S., Ershov A.V. Clinical example of percutaneous nephrolitolapaxy of a complete coral-shaped stone in a patient with lumbar kidney dystopia. Siberian Medical Review. 2021;6:94–98.
- Vatazin A.V., Zulkarnaev A.B. Kidney transplantation as the optimal treatment for chronic kidney disease. Medical case. 2013;3:47–52.
- Berezhnoy A.G., Vinnik Yu.S., Dunaevskaya S.S., Antyufrieva D.A. Possibilities to predict the development of inflammatory complications of the postoperative period in patients with urolithiasis. Bulletin of new medical technologies. 2019;2:109–113.
- Garsiya G.G., Kharden P., Chapmen D. The Importance of Kidney Transplantation in the World. Doctor. 2012;6: 6-8.
- Lubennikov A.E., Trushkin R.N., Kantimerov D.F., Isaev T.K., Artyukhina L.Yu. Nephrectomy in patients with autosomal dominant polycystic kidney disease following kidney transplantation. Experimental and clinical urology. 2020;5(13):126–131.
- Augustine J. Kidney transplant: New opportunities and challenges. Cleve Clin J Med. 2018.;85(2):138–144. doi: 10.3949/ccjm.85gr.18001.
- Timsit M.O., Kleinclauss F., Thuret R. History of kidneytransplantation surgery. Prog Urol. 2016;26(15):874-881. doi: 10.1016/j.purol.2016.08.003.
- Territo A., Mottrie A., Abaza R., Rogers C., Menon M., Bhandari M., Ahlawat R., Breda A. Robotic kidney transplantation: current status and future perspectives. Minerva Urol Nefrol. 2017;69(1):5–13. doi: 10.23736/S0393-2249.16.02856-3.
- Shebel H.M., Akl A., Dawood A., El-Diasty T.A., Shokeir A.A., Ghoneim M.A. Power doppler sonography in early renal transplantation: does it differentiate acute graft rejection from acute tubular necrosis? Saudi J Kidney Dis Transpl. 2014;25(4):733–740. doi: 10.4103/1319-2442.134948.
- Yacoubian A.A., Dargham R.A., Khauli R.B. A review of the possibility of adopting financially driven live donor kidney transplantation. Int Braz J Urol. 2018;44(6):1071–1080. doi: 10.1590/S1677-5538.
Supplementary files
![](/img/style/loading.gif)