QUANTITATIVE MINERALOGICAL ANALYSIS AND STRUCTURE OF URINARY STONES IN PATIENTS LIVING IN IVANOVO REGION


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This paper focuses on developing and implementing a method of quantitative mineralogical analysis of urinary stones based on powder diffraction data analysis using 4 Topas (Bruker) software. Mineralogical composition of 100 urinary stones from urolithiasis patients living in Ivanovo region was examined. More than 70% of stones consisted of calcium oxalate monohydrate (COM) and calcium oxalate dihydrate (COD), and their mixtures with hydroxylapatite. Forty four percent of urinary stones consisted of one component (COM, uric acid (UA) or, less frequently, hydroxyapatite (HA); 56% of urinary stones comprised two, three or four components. The most common mineral was COM (more than 70% of cases), the rarest were calcium oxalate trihydrate (COT), brushite and newberrite. The most common combinations of minerals in mixed stones were COM+HA, COM+COD and COM+COD+HA. The texture, the surface composition and its changes in the course of chemolysis in different types of stones were examined using scanning electron microscopy (SEM) and X-ray microanalysis (XRM). Implications for using analytical chemical and physical techniques for the diagnosis and treatment of urolithiasis were discussed.

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作者简介

A. Kustov

G. A. Krestov Institute of Solution Chemistry of the RAS; Ivanovo State Medical University

Email: kustov@isuct.ru
Dr.Chem.Sci., Senior Researcher

A. Strel'nikov

Ivanovo State Medical University

P. Smirnov

G. A. Krestov Institute of Solution Chemistry of the RAS

S. Gusakova

Belarusian State University

Minsk

M. Moryganov

Ivanovo Regional Clinical Hospital

S. Toms

Ivanovo State Medical University; Ivanovo Regional Clinical Hospital

S. Gruzdev

Ivanovo Regional Clinical Hospital

A. Airapetyan

Ivanovo State Medical University

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