Buccal mucosa transplant - the concept of «ideal graft» in surgical management of peyronie’s disease

Introduction. Surgical techniques in managing Peyronie’s disease include plication corporoplasty, plaque incision, grafting and penile prosthesis implantation. The question of an ideal transplant for corporoplasty remains open. Aim. To evaluate the effectiveness of the substitution corporoplasty using buccal mucosa transplant (BMT) in treating Peyronie’s disease. Materials and methods. From January 2011 to February 2016, 28 patients with stable stage Peyronie’s disease underwent substitution coroproplasty using BMT (incision and grafting). The mean age of patients was 54.8±6.2 years. All patients completed an IIEF-5 questionnaire and underwent a standard preoperative examination: anamnesis, physical examination, penile duplex pharmaco-ultrasonography and penile fixation photography to assess the type and angle of curvature. The average angle of penile curvature was 82.8° (45-120°). All patients underwent incision and grafting using BMT; in 5 patients additionally the plication of the penile tunica albuginea was performed. Follow-up examinations were concluded at 3, 6 and 12 months and more after surgery. Results. Median follow-up was 30 months. Postoperative penile straightening was achieved in 93% of patients. The duplex peak systolic velocity of the right and left cavernosal arteries improved from 42.59 to 45.64 cm/s and from 34.55 to 43.48 cm/s, respectively (p<0.05). Conclusion. Penile corproroplasty using BMT is a safe and effective method of treating patients with Peyronie’s disease. Follow-up clinical and instrumental examination showed no impairment of the erectile function or penile hemodynamics.

tunica albuginea plaque, penile curvature, Peyronie’s disease, corproroplasty, buccal mucosa transplant