Stent-associated urosepsis, personalized bacteriophage therapy
- 作者: Perepanova T.S.1, Kazachenko A.V.1, Mesropyan S.A.1, Antonova V.E.1, Nazirov M.R.1, Malova Y.A.1, Lyubchenko L.N.1
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隶属关系:
- N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center
- 期: 编号 4 (2024)
- 页面: 97-102
- 栏目: Clinical case
- URL: https://journals.eco-vector.com/1728-2985/article/view/636302
- DOI: https://doi.org/10.18565/urology.2024.4.97-102
- ID: 636302
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详细
In the era of antibiotic resistance, strict control of foci of infection (for example, a long-term stent) and adherence to the timing of drainage removal are necessary.
The spread of pan-resistant pathogens requires the development of effective alternative antimicrobial measures, in particular, bacteriophage therapy.
A clinical case of a 42-year-old patient with a closed spinal cord injury, lower paraplegia, pelvic organs dysfunction, post-traumatic right ureteral stricture, and right kidney stones is presented in the article.
The patient developed stent-associated urosepsis due to pan-resistant Klebsiella pneumonia after endoscopic removal of a long-term right ureteral stent (over 3 months) with endotoxic shock, disseminated intravascular coagulation syndrome and wound sepsis, which was treated using personalized local bacteriophage therapy.
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作者简介
T. Perepanova
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center
编辑信件的主要联系方式.
Email: perepanova2003@mail.ru
PhD, MD, Professor, Head of Infectious and Inflammatory Diseases and Clinical Pharmacology Panel of the Department of General and Reconstructive Urology
俄罗斯联邦, MoscowA. Kazachenko
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center
Email: avknii@mail.ru
ORCID iD: 0000-0003-3198-5933
PhD, MD, Deputy Director of Clinical Work
俄罗斯联邦, MoscowS. Mesropyan
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center
Email: perepanova2003@mail.ru
Acting Head of the Department of Anesthesiology and Resuscitation
俄罗斯联邦, MoscowV. Antonova
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center
Email: perepanova2003@mail.ru
PhD, Head of the Transfusiology Department
俄罗斯联邦, MoscowM. Nazirov
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center
Email: nazirov84@mail.ru
Head of the Clinical and Diagnostic Laboratory
俄罗斯联邦, MoscowYu. Malova
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center
Email: perepanova2003@mail.ru
Specialist of Organizational and Methodological Department
俄罗斯联邦, MoscowL. Lyubchenko
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center
Email: perepanova2003@mail.ru
PhD, MD, Professor, Head of the Department of Molecular Genetics and Cellular Technologies
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