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编号 3 (2012)
- 年: 2012
- 文章: 23
- URL: https://journals.eco-vector.com/1728-2985/issue/view/6757
Articles
INFECTIOUS GENESIS OF NEPHROLITHS (ELECTRON-MICROSCOPIC STUDY)
摘要
Scanning electron microscopy and x-ray microstructural analysis were employed in the study of nephroliths from patients suffering from nephrolithiasis. Bacterial biofilms, urease producing microorganisms, alkaline reaction of the urine are basic factors for local urine crystallization, formation of the base of the nephroliths and its rigid fixation to the pelvic mucosa. Mechanic trauma of the pelvic tissues by the concrement results in destruction of the pelvic mucosa epithelium at the site of the nephrolith. Subsequent inflammation in the underlying connective tissue contributes to formation of connective tissue commissures fixing the conrement in the kidney. It is shown that bacteria as a part of a biofilm are capable to persist in nephroliths for a long time. Destruction of the stones during operation or lithotripsy can trigger activation of growth of bacteria integrated in the biofilm and cause septic complications. Preservation of commissures with elements of the destroyed stone after lithotripsy or surgical removal is one of the leading causes of recurrent nephrolithiasis.
Urologiia. 2012;(3):4-7
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TREATMENT AND METAPHYLAXIS OF URATE AND MIXED UROLITHIASIS
摘要
We estimated the efficacy of combined treatment and metaphylaxis of urate and mixed urolithiasis in 87 patients aged 18-87 years. The patients were divided into two groups: 68 patients of group 1 (the size of the concrements between 5-25 mm) have undergone parenteral litholysis of the drug trometamol N and metaphylaxis with biologically active additives prolit and urisan; 19 patients of group 2 have undergone extracorporeal shock-wave lithotripsy with parenteral litholysis and metaphylaxis by using biologically active additives prolit septo and urisan. Positive results were achieved in all the patients. In group 1 the concrements dissolved completely. In group 2 small fragments up to 4 mm eliminated after partial solution.
Urologiia. 2012;(3):7-10
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SYSTEMIC METABOLIC PATHOGENETIC FACTORS OF AFFECTION OF THE SOLITARY KIDNEY IN MALES (A PILOT TRIAL)
摘要
Our pilot trial demonstrates high prevalence of solitary kidney (SK) diseases in men (82.7%). Present-day SK diseases are often accompanied with marked systemic metabolic disorders (obesity, dyslipidemia, androgen deficiency). We found correlations between obesity and incidence of acid urine urolithiasis of the SK, between type II diabetes mellitus, obesity and SK cystic disease. SK men’s glomerular filtration rate depends on the level of total testosterone in blood. We believe that early detection and pathogenetic correction of dyslipidemia, obesity and androgen deficiency in SK men may be key prophylactic factors of SK diseases which often entail development of chronic renal failure.
Urologiia. 2012;(3):11-14
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CONDITION OF THE URINARY TRACT AND THE KIDNEYS IN FEMALES WITH PROLAPSE AND DESCENT OF THE INTERNAL GENITALIA
摘要
Excretory urography (EU), retrograde cystography (RC), static and dynamic pelvic MRT, renoradiography (RRG) were performed in 82 females with descent and prolapse of the internal genitalia. The above examination identified four degrees of the urinary bladder descent. The latter descent of the third and fourth degree caused ureteral obstruction in 48.1 and 87.1% cases, respectively, renal dysfunction in 81.5 and 100% cases, respectively. Static and dynamic pelvic MRT proved to be the most informative methods of examination of the urinary bladder and urethra in females with prolapse and descent of the internal genitalia.
Urologiia. 2012;(3):14-19
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CELLULAR CHANGES IN THE PARAURETHRAL ZONE OF THE EXPERIMENTAL ANIMALS IN EXPOSURE TO COLLOST GEL
摘要
An experimental trial of the collagen gel collost was made on Wistar white female rats aged 68 and 30-36 months. 7 and 15% collost gel (the first Russian collagen gel produced from cattle skin) was implanted in paraurethral region of the animals. The connective tissue cells in the zone of collost gel injection was studied histologically, immunohistochemically, electron microscopically. The examinations revealed differences in the content of the connective tissue in the injection zone depending on a collagen concentration and the age of the animal. The findings suggest that 15% collost gel implantation in the form of a paraurethral injection may be effective in females suffering from stress urinary incontinence for narrowing urethral lumen and preventing spontaneous voiding in response to a rise of intraabdominal pressure.
Urologiia. 2012;(3):19-22
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ALTERATION OF VHL GENE IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA
摘要
Blocks of preparations from 22 patients with metastatic renal cell carcinoma on target therapy were studied. The patients were examined for mutations/methylation of VHL gene. The mutations were detected in 10(45.5%) of 22 patients, VHL methylation was found in 1 (4.5%) patient. Overall survival was 36.4 and 66.7% in the groups of patients with and without gene VHL alteration, respectively. Progression-free survival was 47.6 and 57.1%, respectively (p=0.619), relapse-free survival — 63.6 and 45.5%, respectively (p=0.682), progression was registered in 36.4 and 54.5%, respectively (p=0.682). Gene VHL inactivation had no effect on prognosis of the disease and results of anti-angiogenic therapy.
Urologiia. 2012;(3):22-27
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INTERNAL OPTIC URETHROTOMY IN URETHRAL STRICTURES COMPLICATES SUBSEQUENT RECONSTRUCTIVE SURGERY
摘要
The results of open reconstructive operations performed in 86 patients with traumatic urethral stricture show that the efficacy of these operations and frequency of complications are lower in using urethroplasty as a primary treatment while primary internal optic urethrotomy significantly reduces possibility of effective surgery without complications.
Urologiia. 2012;(3):27-30
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LONG-TERM RESULTS OF PROSTATIC PHOTOSELECTIVE VAPORIZATION IN THE TREATMENT OF PROSTATIC ADENOMA
摘要
Assessment of long-term efficacy and complications of prostatic photoselective vaporization ( Green Light PV (tm) device, Laserscope®, 80W; laser cystoscope, Olympus) was performed in 40 patients with prostatic adenoma (PA) treated in 2005-2006. Mean follow-up was 30.6±16.6 (5.2-60.6) months, time of operation — 52.4 min, intraoperative blood loss — 52 ml maximum, duration of bladder draining with catheter — 1.15 days. For 12 postoperative months IPSS and QoL declined, then for up to 60 months these parameters went up. An 11-month postoperative follow-up recorded a 68.6% maximal decrease in prostatic volume (the size of the prostate decreased to 22.6 cm 3), but after 4 years this volume increased by 24.6% to 38.8 cm 3. Qmax increased more actively during postoperative year 1 and reached maximal value to postoperative month 36. Residual urinary volume fell to initial 95.7 ml to minimal 24.8 ml on follow-up month 12. Mean quantity of energy reached 206±94 (2.4619.0 kJ. Eleven patients had to take oral anticoagulants without any serious intra- or postoperative complications. Recurrent adenoma rose in 4 patients, urethral stricture — in 6.8% patients, cervical bladder sclerosis was found in 3.6% cases. Prostatic cancer development was not registered. Thus, prostatic photoselective vaporization is a safe and efficave procedure in PA treatment.
Urologiia. 2012;(3):31-33
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PILOT RESULTS OF PROSTATIC ADENOMA TREATMENT WITH DIODE LASER MEDILAS D UROBEAM IN THE UKRAINE
摘要
Pilot results of prostatic adenoma treatment with diode laser (940 nm) in 94 patients showed high efficacy of laser vaporization of the prostate. The effect was achieved in all the patients in minimal number of complications and in satisfactory tolerance of the surgery. Laser vaporization has some advantages over standard treatment (TUR) and is a method of choice in small and middle-size adenomas. In large adenoma good results were obtained in combination of laser vaporization with bipolar TUR.
Urologiia. 2012;(3):34-37
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RESULTS OF MONOPOLAR VERSUS QUASIBIPOLAR TRANSURETHRAL RESECTION OF THE PROSTATE AND URINARY BLADDER
摘要
We compared efficacy and safety of mono- vs quasibipolar transurethral resection (TUR) for 198 patients treated with TUR. The patients were randomized into two groups by the TUR variant: monoor quasibipolar. Comparison of pre- and postoperative examinations data in the above two groups demonstrated: blood sodium decreased more in patients from monopolar TUR group, the absence of TUR-syndrome and less frequent and severe symptoms of obturator nerve irritation after quasibipolar TUR. Use of salt solution in quasibipolar TUR allowed us to avoid such a severe postoperative complication as TUR-syndrome. Thus, transurethral resection in physiological solution is an operation of choice in surgical treatment of prostatic adenoma and superficial cancer of the urinary bladder.
Urologiia. 2012;(3):38-41
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DIAGNOSTIKA I LEChENIE OSLOZhNENNOY ANGIOMIOLIPOMY POChKI
Urologiia. 2012;(3):42-44
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DVA NABLYuDENIYa SMORShchIVANIYa MOChEVOGO PUZYRYa POD VOZDEYSTVIEM MIKOBAKTERIY TUBERKULEZA RAZNOGO VIDA
Urologiia. 2012;(3):44-47
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OPYT EFFEKTIVNOY GORMONOKhIMIOTERAPII BOL'NOGO RAKOM PREDSTATEL'NOY ZhELEZY STADII T4N1M0
Urologiia. 2012;(3):47-50
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MNOZhESTVENNYE KISTY PRIDATKA I YaIChKA, SIMULIROVAVShIE KhRONIChESKIY EPIDIDIMIT
Urologiia. 2012;(3):50-51
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OPTIChESKAYa DIAGNOSTIKA MYShEChNO-NEINVAZIVNOGO RAKA MOChEVOGO PUZYRYa
Urologiia. 2012;(3):52-57
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MESTO FITOTERAPII V LEChENII MOChEKAMENNOY BOLEZNI
Urologiia. 2012;(3):58-61
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BCG-TERAPIYa PRI RAKE MOChEVOGO PUZYRYa — PLYuSY I MINUSY
Urologiia. 2012;(3):62-65
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EVOLYuTsIYa OPERATIVNOGO LEChENIYa NEFROLITIAZA
Urologiia. 2012;(3):66-71
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PRIMENENIE SILODOZINA DLYa LEChENIYa BOL'NYKh ADENOMOY PREDSTATEL'NOY ZhELEZY
Urologiia. 2012;(3):71-74
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FIZIChESKIE FAKTORY V LEChENII KhRONIChESKOGO ABAKTERIAL'NOGO PROSTATITA (SINDROMA KhRONIChESKOY TAZOVOY BOLI)
Urologiia. 2012;(3):74-78
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Retsenziya na uchebnik B. K. Komyakova "Urologiya" Geotar-Media, Moskva, 2011, M. 464 s
Urologiia. 2012;(3):79-79
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VLADIMIR NIKOLAEVICh ZhURAVLEV (k 70-letiyu so dnya rozhdeniya)
Urologiia. 2012;(3):80-80
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PAMYaTI ALEKSANDRA LEONOVIChA ShABADA
Urologiia. 2012;(3):81-81
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