VASCULAR DEMENTIA: PATHOGENESIS, DIAGNOSIS AND TREATMENT


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Abstract

The article reviews the pathogenetic, clinical and therapeutic aspects of vascular dementia. The heterogeneity of this condition is emphasized. It is noted that pathological changes in the brain and clinical manifestations of these changes are characterized by certain "cerebral reserve". In contrast to Alzheimer's disease, mnestic disorders only are rarely dominate in the clinical performance of vascular lesions of the brain. The author presented data for the treatment of vascular dementia. Response to treatment should be carefully evaluated for each patient, given the relatively frequent occurrence of paradoxical reactions and side effects of therapy.

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I V Damulin

I Damulin

References

  1. Буссер М.Г., Жутель А., Шабриа Х. и соавт. ЦАДАСИЛ - церебральная аутосомно-доминантная артериопатия с субкортикальными инфарктами и лейкоэнцефалопатией // Неврологогический журнал. 1997. № 3. С. 20-25.
  2. Дамулин И.В. Дисциркуляторная энцефалопатия в пожилом и старческом возрасте. Дисс. докт. мед. наук. М., 1997. 32 с.
  3. Калашникова Л.А., Бодарева Э.А., Кашина Е.М. и соавт. Нарушения высших психических функций и деменция при синдроме Снеддона // Неврологический журнал. 1998. № 4. С. 15-19
  4. Левин О.С. Клинико-магнитнорезонанснотомографическое исследование дисциркуляторной энцефалопатии с когнитивными нарушениями. Дисс. канд. мед. наук. М., 1996. 24 с.
  5. Яхно Н.Н. Когнитивные расстройства в неврологической клинике // Неврологический журнал 2006. Т. 11. № 1. С. 4-13.
  6. Яхно Н.Н., Левин О.С., Дамулин И.В. Сопоставление клинических и МРТ-данных при дисциркуляторной энцефалопатии. Сообщение 2. Когнитивные нарушения // Неврологический журнал 2001. Т. 6. № 3. С. 10-18.
  7. Bowler JV, Hachinski V. Current criteria for vascular dementia - a critical appraisal. /In: Vascular Cognitive Impairment: Preventable Dementia. Oxford University Press 2003;1-11.
  8. Chimowitz MI, Thompson DW, Furlan AJ. Common vascular problems in office practice. /In: Office Practice of Neurology. Churchill Livingstone 1996;334-41.
  9. del Ser T, Martinez-Lage P. Associated neurological features. In: Vascular Cognitive Impairment. 2002;253-64.
  10. Erkinjuntti T, Gauthier S. Vascular cause of cognitive impairment - the perspective. In: Vascular Cognitive Impairment. 2002;643-51.
  11. Gustafson L, Passant U. Clinical pathological correlates. In: Cerebrovascular Disease, Cognitive Impairment and Dementia. 2004;197-210.
  12. Hachinski VC, Lassen NA, Marshall J. Multi-infarct dementia. A case of mental deterioration in the elderly. Lancet 1974;2:207-10.
  13. Leys D, Henon H, Pasquier F. The role of cerebral infarcts in vascular dementia. In: Research and Practice in Alzheimer's Disease 2001;5:123-8.
  14. Leys D, Englund E, Erkinjuntti T. Vascular dementia. In: Evidence-based Dementia Practice 2002;260-287.
  15. Reijmer YD, Hooijmans CR, Basten EAP, et al. Dietary lipids influence spatial memory, cerebral blood volume and amyloid pathology in the APP/PSI mouse model of Alzheimer's disease. In: Fifth International Congress on Vascular Dementia. Final Program & Abstracts 2007;94-5.
  16. Rocca WA, Knopman DS. Prevalence and incidence of vascular dementia. In: Vascular Cognitive Impairment: Preventable Dementia 2003;21-32.
  17. Roman GC. Facts, myths, and controversies in vascular dementia. J Neurol Sci 2004;226:49-52. Roman GC. Clinical Forms of Vascular Dementia. In: Vascular Dementia: Cerebrovascular Mechanisms and Clinical Management. 2005;7-21.
  18. Russell D. Invasive medical procedures and silent cerebral ischemia. In: Fifth International Congress on Vascular Dementia. Final Program & Abstracts 2007;63-4.
  19. Skoog I, Aevarsson O. Epidemiology of vascular dementia in Europe. In: Cerebrovascular Disease, Cognitive Impairment and Dementia 2004;35-48.
  20. Tomlinson BE, Blessed G, Roth M. Observation on the brains of demented old people. J Neurol Sci 1970;11:205-242.
  21. Wahlund LO. Brain imaging and vascular dementia. In: Vascular Dementia. Etiological, Pathogenetic, Clinical and Treatment Aspects. 1994;65-68.
  22. Yamazaki T, Utsumi H, Komatsu H, et al. Frontal hypoperfusion as a possible participation of ischemic changes in AD patients. In: Fifth International Congress on Vascular Dementia. 2007;93-4.

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