GENITAL MYCOPLASMOSIS AND NONCARRYING OF PREGNANCY


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Abstract

1120 pregnant women were examined in order to determine the impact of urogenital mycoplasmosis on pregnancy. In 56.5% of cases urogenital mycoplasmas (Ureaplasma urealyticum, Mycoplasma hominis, or both of them) were identified: in 31.7% - only the urogenital mycoplasma, in 64.2% - urogenital mycoplasma in conjunction with other pathogenic microflora, in 4.1% - in conjunction with chlamydia. The analysis of the data showed that urogenital mycoplasma is implicated in the development of a number of pathological processes during pregnancy. Timely etiopathogenetic antibiotic therapy at 17 to 18 weeks of gestation led to reduction of inflammation in the placental system, the normalization of its function, which was reflected in a significant reduction in the frequency of pregnancy complications, optimization of perinatal outcomes.

References

  1. Балабанов Д.Н. Антигенемия при урогенитальных микоплазменных инфекциях. Автореф. дисс. канд. мед. наук. М., 2009. 31 с.
  2. Кисина В.И., Ширшова Е. В. Инфекции, передающиеся половым путем у женщин: Существует ли связь генитальных микоплазм с патологией органов мочеполовой системы? // Сonsilium-medicum. 2005. Т. 7.
  3. Салманидина Д.Р. Клинико-патогенетические особенности раннего неонатального периода детей у матерей с микоплазменной и смешанной инфекцией. Автореф. дисс. канд. мед. наук. Казань, 2001. 14 с.
  4. Серов В.Н., Михайлов А.В., Гасанова Т.А. и соавт. Результаты инфекционного скрининга беременных и новорожденных в Саратовской области. Пленум Российской ассоциации акушеров-гинекологов "Инфекции в акушерстве, гинекологии и перинатологии". Сборник научных трудов. Саратов, 1999. С. 233-40.
  5. Сидельникова В.М. Инфекция как фактор риска невынашивания беременности // Гинекология. 2008.Т. 10. № 5. С. 28-30.
  6. Global strategy for the prevention and control of sexually transmitted infection: 2006-2015, World Health Organization, Department of Reproductive Health and Research, 2006
  7. Aujard Y, Maury L, Doit C, et al. Ureaplasma urealyticum and Mycoplasma hominis infections in newborns: personal data and review of the literature. Arch Pediatr 2005;12(l):12-18.
  8. Benstein BD, Crouse DT, Shanklin DR, et al. Ureaplasma in lung. 2. Association with bronchopulmonary dysplasia in premature newborns. Exp Mol Pathol 2003;75(2):171-77.
  9. Berger A, Witt A, Haiden N, et al. Intrauterine infection with Ureaplasma species is associated with adverse neuromotor outcome at 1 and 2 years adjusted age in preterm infants. J Perinat Med 2009;37(1):72-8.
  10. Katz B, Patel P, Duffy L, et al. Characterization of Ureaplasmas Isolated from Preterm Infants with and without Bronchopulmonary Dysplasia. J Clin Microbiol 2005;(43):4852-54.
  11. Bujold E, Morency AM, Rallu F, et al. Bacteriology of amniotic fluid in women with suspected cervical insufficiency. J Obstet Gynaecol Can 2008;30(10):882-87.
  12. Czeizel AE, Rockenbauer M, Olsen J, et al. A case control teratological study of spiramycin, roxithromycin, oleadomycin and josamycin. Acta Obstet Gynecol Scand 2000;79(3):234-37.
  13. Daniel G, Keeler SM., Orion A, et al. Is midtrimester short cervix a sign of intraamniotic inflammation. Amer J Obst Gyn 2009;200(4 ):1-5.
  14. Egawa T, Morioka I, Morisawa T, et al. Ureaplasma urealyticum and Mycoplasma hominis presence in umbilical cord is associated with pathogenesis of funisitis. Kobe J Med Sci. 2007;53(5):241-9.
  15. Mannello F.. Serum or Plasma Samples? Arteriosclerosis, Thrombosis, and Vascular Biology 2008;28:611.
  16. Goldenberg RL, Andrews WW, Goepfert AR. The Alabama Preterm Birth Study: umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infants. Am J Obstet Gynecol 2008;198(1):1-5.
  17. Harada K, Tanaka H, Komori S, et al. Vaginal infection with Ureaplasma urealyticum accounts for preterm delivery via induction of inflammatory responses. Microbiol Immunol. 2008;52(6):297-304.
  18. Hecht JL, Onderdonk A, Delaney M, et al. ELGAN Study Investigators. Characterization of chorioamnionitis in 2nd-trimester C-section placentas and correlation with microorganism recovery from subamniotic tissues. Pediatr Dev Pathol. 2008;11(1):15-22.
  19. Kacerovsky M, Boudys L. Preterm premature rupture of membranes and Ureaplasma urealyticum. Ceska Gynekol 2008;73(3):154-59.
  20. Marodi L. Neonatal innate immunity to infectious agents. Infect Immun 2006;74(4):1999-2006
  21. Lee SE, Romero R, Jung H, et al. The intensity of the fetal inflammatory response in intraamniotic inflammation with and without microbial invasion of the amniotic cavity. Am J Obstet Gynecol 2007;197(3):1-6.
  22. Lee SE, Romero R, Park CW, et al. The frequency and significance of intraamniotic inflammation in patients with cervical insufficiency. Am J Obstet Gynecol 2008;198(6):1-8.
  23. Moss TJ, Knox CL, Kallapur SG, et al. Experimental amniotic fluid infection in sheep: effects of Ureaplasma parvum serovars 3 and 6 on preterm or term fetal sheep. Am J Obstet Gynecol 2008;198(1):1-8.
  24. Moss TJ, Nitsos I, Knox CL, et al. Ureaplasma colonization of amniotic fluid and efficacy of antenatal corticosteroids for preterm lung maturation in sheep. Am J Obstet Gynecol 2009;200(1):1-6.
  25. Normann E, Lacaze-Masmonteil T, Eaton F, et al. A novel mouse model of Ureaplasma-induced perinatal inflammation: effects on lung and brain injury.. Pediatr Res 2009 Apr;65(4):430-6.
  26. Novy MJ, Duffy L, Axthelm MK, et al.Ureaplasma parvum or Mycoplasma hominis as sole pathogens cause chorioamnionitis, preterm delivery, and fetal pneumonia in rhesus macaques. Reprod Sci 2009;16(1):56-70.
  27. Oue S, Hiroi M, Ogawa S, et al. Association of gastric fluid microbes at birth with severe bronchopulmonary dysplasia. Arch Dis Child Fetal Neonatal Ed 2009;94(1):17-22.
  28. Peltier MR, Tee SC, Smulian JC. Effect of progesterone on proinflammatory cytokine production by monocytes stimulated with pathogens associated with preterm birth. Am J Reprod Immunol 2008;60(4):346-53.
  29. Randelovic G, Kocic B, Miljkovic-Selimovic B, et al. High-density cervical Ureaplasma urealyticum colonization in pregnant women as a risk factor for premature rupture of membranes Vojnosanit Pregl 2006;63(8):737-41.
  30. Gomez R, Romero CR, Nien JK, et al. Idiopathic vaginal bleeding during pregnancy as the only clinical manifestation of intrauterine infection. The Journal of Maternal-Fetal & Neonatal Medicine 2005;18:31-37.
  31. Romero R, Garite TJ. Twenty percent of very preterm neonates (23-32 weeks of gestation) are born with bacteremia caused by genital Mycoplasmas. Am J Obstet Gynecol. 2008;198(1):1-3.
  32. Keeler S, Kiefer D, Rust O, et al. A novel method of assessing cervical collagen integrity utilizing image segmentation analysis. Amer J Obst Gynecol 2008(199):227-27.
  33. Viscardi RM, Hashmi N, Gross GW, et al. Incidence of invasive Ureaplasma in VLBW infants: relationship to severe intraventricular hemorrhage. J Perinatol 2008.
  34. Yoko Honma, Yukari Yada, et al.Nakamura.Certain type of chronic lung disease of newborns is associated with Ureaplasma urealyticum infection in utero. Pediatr Internat 2007;49(4):479-84.

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