EXPERIENCE OF USE OF NATIVE HEPATOPROTECTOR HEPTOR (ADEMETIONINE) IN PATIENTS WITH ALCOHOLIC LIVER DISEASE
- Authors: Golovanova Y.V1, Golovanova E.V.1
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Affiliations:
- Issue: No 12 (2010)
- Pages: 82-87
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/278517
- ID: 278517
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Abstract
Ademetionine plays an important role in the treatment of alcoholic liver disease (ALD) due to its detoxication, antioxidant, chloretic, cytoprotective (hepatoprotective), antifibrosing and neuroprotective (antidepresant) effects. The article presents results of study aimed to estimation of efficacy and safety of drug Heptor (tablets Ademetionine) manufactured by Joint-Stock Company "Veropharm", Russia, in a combination with parenteral form of Ademetionine (drug Heptral manufactured by "Knoll", Germany) in the treatment of 60 patients with ALD(chronic hepatitis or cirrhosis) in comparison with monotherapy by Heptral (lyophilizate + tablets). 18-day courses of treatment by tablets Heptor and Heptral have shown similar results in regard to time of development of a positive effect and influence for biochemical activity of disease. The profile of safety of Heptor (tablet) is similar to that Heptral (tablet). Thus, Heptor (tablets Ademetionine) can be recommended for treatment of patients with ALD at stages of chronic hepatitis and cirrhosis.
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