THERAPEUTIC EFFICACY OF INTERFERON PREPARATIONS IN THE TREATMENT OF ACUTE BRONCHITIS


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Abstract

A multicenter randomized prospective comparative study was conducted to assess the effectiveness and safety of Genferon® (suppositories) in acute bronchitis patients. Patients were randomized to 3 groups, 50 patient each: the first and second groups were treated with Genferon® or IFN-α with vitamins C and E, respectively, in parallel to the standard management, while patients in the third group have received standard treatment only. It was found that Genferone® addition in acute bronchitis treatment have an apparent therapeutic effect, including decrease of duration of fever, disease symptoms and intoxication as well asdecrease in sick leave duration. Identified evidence of effectiveness, safety and good tolerability of Genferon® suppositories allows recommending this drug for management of acute bronchitis.

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