EFFECTIVENESS OF TADALAFIL IN MEN WITH PREMATURE EJACULATION IN COMBINATION WITH ERECTILE DYSFUNCTION


Cite item

Full Text

Abstract

The article considers the results of study included 85 men with premature ejaculation (PE) and concomitant erectile dysfunction (ED), whose goal was optimization of treatment with phosphodiesterase type 5 (PDE-5) inhibitor - tadalafil. The results have shown that the use of PDE-5 inhibitors in clinical practice enhances the treatment of patients with PE in combination with ED or without ED. Given the pharmacokinetic characteristics of tadalafil, this drug may be considered as the most appropriate PDE-5 inhibitor for the treatment of patients with PE.

References

  1. Perelman MA. A new combination treatment for premature ejaculation: a sex therapist's perspective J Sex Med 2006;3:1004-12.
  2. McMahon CG. Long term results of treatment of premature ejaculation with selective serotonin reuptake inhibitors. Int J Imp Res 2002;14(Suppl. 3):S19.
  3. Symonds T, Roblin D, Hart K, et al. How does premature ejaculation impact a man's life? J Sex Marital Ther 2003;29(5):361-70.
  4. Dunn KM, Croft PR, Hackett GI. Sexual problems: a study of the prevalence and need for health care in the general population. Fam Pract 1998;15(6):519-24.
  5. Waldinger MD. The neurobiological approach to premature ejculatuon. J Urol 2002;168(6):2359-67.
  6. Patrick D, Althof S, Pryor J, et al. Premature ejaculation: An observational study of men and their partners. J Sex Med 2005;2:358-67.
  7. Xin ZC, Choi YD, Rha KH, Choi HK. Somatosensory evoked potentials in patients with premature ejaculation. J Urol 1997;158: 451-55.
  8. Сегал А.С. Пушкарь Д.Ю. Преждевременная эякуляция: определение, рабочая классификация, алгоритм обследования больных и результаты их использования // Урология. 2006. № 3. С. 66-9.
  9. Sotomayor M. The burden of premature ejaculation: The patient's perspective. J Sex Med 2005;2(Suppl. 2):110-4.
  10. Porst H, Buvat J. (eds.) Standard practice in sexual medicine. Oxford, Blackwell Publishing., 2006.
  11. Калинченко С.Ю., Козлов Г.И. Эректильная дисфункция у больных сахарным диабетом. Диагностика. Дифференциальная диагностика. Лечение. М., 2003. 28 с.
  12. Lobik L, Cyrton S, Kravchick S, et al. The effect of sildenafil citrate in the treatment of secondary rapid ejaculation. J Urol 2003;169(4):378-79.
  13. Laumann EO, Nicolosi A, Glasser DB, et al. Sexual problems among women and men aged 40-80 y:prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors. Int J Impot Res 2005;17(1):39-57.
  14. Chen J, Kern-Paz G, Bar-Yoser Y, et al. The role of phosphodiesterase type 5 inhibitors in the management of premature ejaculation: a critical analysis of basic science and clinical data. Eur Urol 2007;52:1331-39.
  15. Waldinger M. Towards evidenced based drug treatment research on premature ejaculation: a critical evaluation of methodology. J Impotence Res 2003;15(5):309-13.
  16. McMahon CG, Touma K. Treatment of premature ejaculation with paroxetine hydrochloride as needed: 2 single-blind placebo controlled crossover studies. J Urol 1999;161(6):1826-30.
  17. McMahon CG, Stuckey BG, Andersen ML, et al. Efficacy of sildenafil citrate (Viagra) in men with premature ejaculation. J Sex Med 2005;2:368-75.
  18. Atan A, Basar MM, Tuncel A, et al. Comparison of efficacy of sildenafil-only, sildenafil plus topical EMLA crem, and topical EMLA-crem-only in treatment of premature ejaculation. Urology 2006;67:388-91.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies