HEPATIC CIRRHOSIS AS OUTCOME OF CHRONIC HEPATITIS C: DIFFICULTIES OF ANTIVIRAL THERAPI


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Abstract

The article considers the indications for antiviral therapy (AVT) of liver cirrhosis against the background of HCV-infection (a combination of pegylated interferon-α and ribavirin). The features of AVT and the difficulties of treatment of such patients, including preparing for a liver transplant operation, are discussed. It is emphasized that patients with compensated liver cirrhosis (Child-Turcotte-Pugh score = 5), particularly with initial signs of portal hypertension - are the only category of this group of patients entitled to AVT in accordance with all the modern guidelines, when AVT is targeted to achieve of sustained virological response.

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