EFFECT OF LOCAL THERAPY OF GONARTHROSIS BY HYALURONIC ACID PREPARATIONS OF VARIOUS MOLECULAR WEIGHTS ON DYNAMICS OF ALGOFUNCTIONAL MEASURES


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Abstract

A comparative analysis of the effectiveness of local therapy of gonarthrosis by hyaluronic acid preparations (HA) of different molecular weight (Fermatron and Sinokrom forte) against the background of oral administration of chondroprotector Teraflex (glucosamine hydrochloride + chondroitin sulfate) was performed. Prospective follow-up of patients after a course of intra-articular injections showed the superiority of preparation of high molecular weight HA Sinokrom forte over preparation of medium molecular weight HA Fermatron for improvement of functional activity of the joints at 6 months. Sustainable pain management at rest and on movement was achieved in the group receiving Fermatron.

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