Fenomen nochnogo kislotnogo proryva na fone lecheniya ingibitorami protonnoy pompy i ego terapevticheskaya korrektsiya


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Abstract

The article discusses the phenomenon of nocturnal acid breakthrough (NAB), which arises against the background of the use of proton pump inhibitors (PPIs) for the treatment of acid-related disorders, especially gastroesophageal reflux disease. Definition of the phenomenon is presented, the mechanism of its development and treatment options are considered. The potentials for the use of PPIs with accelerated antisecretory effect in the treatment of NAB and their difference from omeprazole with delayed release are discussed. The characteristics of the new IPP Omez® Insta are presented, and its effectiveness in the treatment of acid-related disorders and NAB is demonstrated.

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S. A Bulgakov

Email: av22956@akado.ru

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